53 Pages | 6 Exhibits | 2018 Analysis | Forecasts Through 2022 Product Family: Market Reports

This analysis includes a discussion of products, current/forecast markets, competitors, and opportunities in the US, 5EU, Japan, and RoW markets for tissue-engineered skin replacements (epidermal, dermal, and multilayer equivalents, and amniotic tissue grafts) and active wound repair modulators (growth factors, gene therapy agents, and stem cells).


  • The combined global market for tissue-engineered skin replacements and active wound repair modulators totaled more than $1bn in 2017, and is expected to climb at a rate of 6.0% over the next half-decade.
  • The tissue-engineered skin replacements segment accounts for nearly 90% of sales, with the 5EU markets, Japan, and the RoW markets combined accounting for the remaining 10% of sales.
  • The US accounts for nearly 92% of global sales in this market, due to factors including slower adoption of skin replacements in international markets as a result of cultural aversion to the use of cadaveric tissue, concerns regarding disease transmission, and limited reimbursement.
Key Questions Answered
  • What are the key drivers and limiters to the global wound care products market?
  • Which competitors are leading the market and introducing new technology?
  • How are technological advancements impacting market growth?
  • Which areas of the wound care products market are experiencing dynamic growth?
  • How are mergers and acquisitions affecting the markets shares of leading competitors?

Executive Summary
i. Tissue-engineered skin replacements
ii. Active wound repair modulators 
iii. Market analysis 
iv. Major competitors
v. Methodology

Exhibit ES-1: Tissue-engineered skin replacements and active wound repair modulators, market forecast ($m), 2017-22

1. Tissue-Engineered Skin Replacements

1.1 Allografts
1.2 Autografts 
1.3 Xenografts
1.4 Autologous and tissue-engineered skin replacements
	1.4.1 Epidermal equivalent products
	1.4.2 Dermal equivalent products 
	1.4.3 Multilayer equivalent products
	1.4.4 Amniotic tissue grafts 
1.5 Market forecast
1.6 Competitive analysis
1.7 Bibliography 

Exhibit 1-1: Tissue-engineered skin replacements, market forecast, 2017-22
Exhibit 1-2: Tissue-engineered skin replacements market, share by supplier, 2017 

2. Active Wound Repair Modulators

2.1 Growth factors
	2.1.1 Growth factor classification
	2.1.2 Competitors and products
	2.1.3 Market forecast
2.2 Gene therapy agents
2.3 Stem cells
	2.3.1 Types of stem cells
	2.3.2 The role of stem cells in wound healing 
2.4 Other active wound repair modulators and pharmaceuticals
	2.4.1 Antibiotics and anti-infectives 
	2.4.2 Hormones
	2.4.3 Matrix metalloproteinase enzyme inhibitors 
	2.4.4 Neuropeptides in diabetic wounds
	2.4.5 Other products
2.5 Bibliography 

Exhibit 2-1: Selected growth factors under development for wound healing applications
Exhibit 2-2: The angiogenesis process
Exhibit 2-3: Growth factors, market forecast ($m), 2017-22

Appendix: Company Listing


  1. Acelity
  2. AediCell
  3. Allergan
  4. Amarantus BioScience Holdings
  5. Amniox Medical/TissueTech
  6. Avita Medical
  7. Celularity
  8. Derma Sciences/Integra LifeSciences
  9. Genentech/F. Hoffmann-La Roche
  10. Harvest Technologies/Terumo
  11. Integra LifeSciences
  12. Isto Biologics/Isto Holdings
  13. Kaken Pharmaceutical
  14. Mallinckrodt Pharmaceuticals
  15. Merck
  16. Metasurg/Integra Lifesciences
  17. MiMedx Group
  18. MTF Biologics
  19. Novartis
  20. Nuo Therapeutics
  21. NuTech Medical/Organogenesis
  22. Olympus America/Olympus
  23. Organogenesis
  24. Osiris Therapeutics
  25. Promethean LifeSciences
  26. RegeneRx
  27. Regenerys
  28. Regenicin
  29. Smith & Nephew
  30. Theravance Biopharma
  31. Vericel
  32. Wright Medical Technology/Wright Medical Group
  33. Zimmer Biomet
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