U.S. MARKETS FOR DRUG AND FLUID DELIVERY DEVICES

253 Pages | 73 Exhibits | 2001 Analysis | Forecasts Through 2005

OVERVIEW:
Pharmacological therapy is the preferred treatment method for the management of virtually all common medical disorders that warrant therapeutic intervention. To date, the Food and Drug Administration has cleared approximately 37,000 prescription drug products for marketing in the U.S. These products account for more than 70% of the national consumption of pharmaceuticals.

In the year 2000, U.S. pharmacies processed approximately 2.7 billion prescriptions; total sales of prescription and over-the-counter drugs exceeded $110 billion, and accounted for approximately 10% of national healthcare spending.

Device-based drug delivery technologies that offer the combination of functional characteristics required for the administration of effective pharmacological therapy include injection/infusion systems, transdermal patch preparations, and inhalation systems. In the year 2000, sales of these delivery devices exceeded $7 billion and were involved in the administration of pharmaceutical preparations to more than 120 million patients at U.S. hospitals and alternate care sites.

Major topics in this report from Medtech Insight include analysis of technologies, products, current and forecast markets, competitors, and opportunities in: syringes, pen & jet injectors; volumetric & syringe pumps; ambulatory & disposable pumps; implantable & insulin pumps; enteral pumps & gravity systems; intravascular gravity infusion systems; short peripheral & midline catheters; central venous & peripherally inserted central catheters; implantable ports; transdermal patch-based drug delivery; metered-dose and dry powder inhalers; and nebulizers & inhaled insulin systems.

TABLE OF CONTENTS:

EXECUTIVE SUMMARY

     i. Drug and Fluid Injection/Infusion Systems

     ii. Transdermal Patch-Based Drug Delivery Systems

     iii. Inhaled Drug Therapy Systems

 

1. ESTABLISHED METHODS OF DRUG DELIVERY

     1.1 Oral Administration

     1.2 Transdermal Delivery

     1.3 Transmucosal Administration

     1.4 Pulmonary Administration

     1.5 Injection and Infusion

          1.5.1 Needle Injection

          1.5.2 Jet Injection

          1.5.3 Intravascular Infusion

          1.5.4 Intraspinal Infusion

          1.5.5 Intra-Operative Site Infusion

          1.5.6 Intraperitoneal/Transperitoneal Infusion

 

2. DRUG AND FLUID DELIVERY BY INJECTION/INFUSION METHODS

     2.1 Drug Injection/Infusion Devices

     2.2 Major Drug Injection/Infusion Applications

          2.2.1  Anesthesia Delivery

          2.2.2  Antibiotic/Antiviral Therapy

          2.2.3  Bone Marrow and Organ Transplant Support Therapy

                    2.2.3.1 Bone Marrow Transplantation

                    2.2.3.2 Organ Transplantation

          2.2.4  Cardiovascular Disease Infusion Therapy

                    2.2.4.1 Anticoagulation and Thrombolysis

                    2.2.4.2 Treatment of Congestive Heart Failure

          2.2.5  Chemotherapy

          2.2.6  Diabetes Management

          2.2.7  Hydration Therapy

          2.2.8  Nutritional Support

                    2.2.8.1 Total Parenteral Nutrition

                    2.2.8.2 Enteral Nutrition

          2.2.9   Pain Management/Patient-Controlled Analgesia

          2.2.10 Transfusion/Replacement Therapy

          2.2.11 Other Infusion-Based Drug Therapies

                    2.2.11.1 Biotechnology Therapies

                                 2.2.11.1.1 Cytokine Therapy

                                 2.2.11.1.2 Growth Hormone Therapy

                                 2.2.11.1.3 Interferon Therapy

                    2.2.11.2 Infertility Therapy

                    2.2.11.3 Management of High-Risk Pregnancies

                    2.2.11.4 Perinatal Therapy

     2.3 Injection/Infusion Therapy Technologies and Markets

          2.3.1  Syringe Technology and Product Markets

                    2.3.1.1 Standard Multipurpose Syringes

                    2.3.1.2 Safety Syringes

                    2.3.1.3 Insulin Syringes

                    2.3.1.4 Market Forecast

                    2.3.1.5 Competitive Analysis

          2.3.2  Insulin Pen Technology and Product Market

                    2.3.2.1 Market Forecast

                    2.3.2.2 Competitive Analysis

          2.3.3  Needleless Jet Injector Technology and Product Market

                    2.3.3.1 Market Forecast

                    2.3.3.2 Competitive Analysis

          2.3.4  Infusion Pump Technology and Product Markets

                    2.3.4.1 Volumetric Pumps

                                2.3.4.1.1 Market Forecast

                                2.3.4.1.2 Competitive Analysis

                    2.3.4.2 Syringe Pumps

                               2.3.4.2.1 Market Forecast

                               2.3.4.2.2 Competitive Analysis

                    2.3.4.3 Ambulatory Pumps

                               2.3.4.3.1 Market Forecast

                               2.3.4.3.2 Competitive Analysis

                    2.3.4.4 Disposable Pumps

                               2.3.4.4.1 Market Forecast

                               2.3.4.4.2 Competitive Analysis

                    2.3.4.5 Implantable Pumps

                               2.3.4.5.1 Market Forecast

                               2.3.4.5.2 Competitive Analysis

                    2.3.4.6 External Insulin Pumps

                               2.3.4.6.1 Market Forecast

                               2.3.4.6.2 Competitive Analysis

                    2.3.4.7 Enteral Pumps and Gravity Systems

                               2.3.4.7.1 Market Forecast

                               2.3.4.7.2 Competitive Analysis

                    2.3.4.8 Intravascular Gravity Infusion Systems

                               2.3.4.8.1 Market Forecast

                               2.3.4.8.2 Competitive Analysis

          2.3.5  Vascular Access Technologies and Product Markets

                    2.3.5.1 Short Peripheral Catheters

                               2.3.5.1.1 Market Forecast

                               2.3.5.1.2 Competitive Analysis

                    2.3.5.2 Midline Catheters

                               2.3.5.2.1 Market Forecast

                               2.3.5.2.2 Competitive Analysis

                    2.3.5.3 Peripherally Inserted Central Catheters

                               2.3.5.3.1 Market Forecast

                               2.3.5.3.2 Competitive Analysis

                    2.3.5.4 Central Venous Catheters

                               2.3.5.4.1 Market Forecast

                               2.3.5.4.2 Competitive Analysis

                    2.3.5.5 Implantable Ports

                               2.3.5.5.1 Market Forecast

                               2.3.5.5.2 Competitive Analysis

 

3. TRANSDERMAL DRUG DELIVERY

     3.1 Transdermal Patch Technology

          3.1.1 Transdermal Active Transport Systems

     3.2 Transdermal Patch Applications and Product Markets

          3.2.1 The Management of Angina Pectoris and Hypertension

                   3.2.1.1 Nitroglycerin and Clonidine Patch Products

                   3.2.1.2 Market Forecast

                   3.2.1.3 Competitive Analysis

          3.2.2  Estrogen Replacement Therapy

                   3.2.2.1 Estrogen Patch Products

                   3.2.2.2 Market Forecast

                   3.2.2.3 Competitive Analysis

          3.2.3 Smoking Cessation

                   3.2.3.1 Nicotine Replacement Therapy Products

                              3.2.3.1.1 Nicotine Patch

                              3.2.3.1.2 Nicotine Gum

                              3.2.3.1.3 Nicotine Inhaler

                              3.2.3.1.4 Nicotine Nasal Spray

                              3.2.3.1.5 BUPROPION

                   3.2.3.2 Market Forecast

                   3.2.3.3 Competitive Analysis

          3.2.4 Pain Management Therapy

                   3.2.4.1 Cancer Pain

                   3.2.4.2 Postherpetic Neuralgia

                   3.2.4.3 Analgesic Patch Products

                              3.2.4.3.1 Duragesic Fentanyl Patch

                              3.2.4.3.2 Lidoderm Lidocaine Patch

                   3.2.4.4 Market Forecast

                   3.2.4.5 Competitive Analysis

 

4. INHALATION DRUG THERAPY

     4.1 Chronic Obstructive Respiratory Disorders Targeted by

           Inhalation Therapy

          4.1.1 Bronchial Asthma

          4.1.2 Chronic Bronchitis

          4.1.3 Emphysema

          4.1.4 Cystic Fibrosis

     4.2 Inhalation Drug Therapy for Chronic Obstructive

           Respiratory Disorders

          4.2.1 Bronchodilators

          4.2.2 Anti-Inflammatory Agents

     4.3 Inhalation Drug Therapy Delivery Technology

          4.3.1 Metered-Dose Inhalers

                   4.3.1.1 Breath-Actuated Metered-Dose Inhalers

                   4.3.1.2 Chlorofluorocarbon-Free Metered-Dose Inhalers

                   4.3.1.3 Spacer Devices

          4.3.2 Dry-Powder Inhalers

          4.3.3 Nebulizers

          4.3.4 Metered-Dose and Dry-Powder Inhalers for the

                  Treatment of Chronic Obstructive Respiratory Disorders

          4.3.5 Emerging Nonrespiratory Applications of Inhalation

                  Drug Therapy

                   4.3.5.1 Inhaled Insulin Technologies

     4.4 Major Inhaled Drug Therapy Systems, Market Analysis

          4.4.1 Market Forecast for Chronic Obstructive Respiratory

                  Disorder Devices

          4.4.2 Market Forecast for Inhaled Insulin Products

          4.4.3 Competitive Analysis

 

5. COMPANY PROFILES

5.1    Abbott Laboratories

5.2    Alaris Medical Systems, Inc.

5.3    Arrow International, Inc.

5.4    Aventis Pharma/Aventis Group

5.5    C.R. Bard, Inc.

5.6    Baxter Healthcare Corporation/Baxter International

5.7    Becton Dickinson and Company

5.8    Bioject Medical Technologies, Inc.

5.9    Boehringer Ingelheim Pharmaceuticals, Inc.

         /Boehringer Ingelheim Group

5.10   Disetronic Medical Systems, Inc./Disetronic Group

         /Disetronic Holding AG

5.11   Endo Pharmaceuticals, Inc.

5.12   Johnson & Johnson

5.13   GlaxoSmithKline

5.14   Horizon Medical Products, Inc.

5.15   I-Flow Corporation

5.16   Kendall Healthcare Products Corporation/Tyco

         International LTD

5.17   Medex/Saint-Gobain Performance Plastics/Saint-Gobain Group

5.18   Medtronic, Inc.

5.19   MiniMed, Inc.

5.20   Novartis Pharmaceuticals Corporation/Novartis AG

5.21   Novo Nordisk Pharmaceuticals, Inc./Novo Nordisk AS

5.22   Schering-Plough Corporation

5.23   SIMS Deltec, Inc./Smith Industries Medical Systems/Smiths Group PLC

 

COMPANY LISTING

 

LIST OF EXHIBITS

 

Exhibit ES-1:  Drug Delivery Products, by Type, Market Forecast, 2000-2005 

Exhibit ES-2:  Injection/Infusion Drug and Fluid Delivery Systems, Market Forecast, 2000-2005 

Exhibit ES-3:  Transdermal Patch Products, Market Forecast, 2000-2005 

Exhibit ES-4:  Dry-Powder and Metered-Dose Inhalers for the Treatment of Chronic Obstructive Respiratory Disorders, and Insulin Delivery Systems, Market Forecast, 2000-2005 

 

Exhibit 1-1:    Advantages and Disadvantages of Common Drug Delivery Modalities 

 

Exhibit 2-1:    Injection/Infusion Drug and Fluid Delivery Systems, Market Forecast, 2000-2005 

Exhibit 2-2:    2001, Selected Safety Syringes 

Exhibit 2-3:    2001, Selected Insulin Syringes 

Exhibit 2-4:    Syringes, Market Forecast, 2000-2005 

Exhibit 2-5:    2000, Syringes Market, Share by Supplier 

Exhibit 2-6:    2001, Selected Insulin Pens 

Exhibit 2-7:    Insulin Pen Products, Market Forecast, 2000-2005 

Exhibit 2-8:    2000, Insulin Pen Products Market, Share by Supplier 

Exhibit 2-9:    2001, Selected Jet Injector Products 

Exhibit 2-10:  Jet Injector Products, Market Forecast, 2000-2005 

Exhibit 2-11:  2000, Jet Injector Products Market, Share by Supplier 

Exhibit 2-12:  Infusion Pump Products, Market Forecast, 2000-2005 

Exhibit 2-13:  2001, Selected Volumetric Pumps 

Exhibit 2-14:  Volumetric Pump Products, Market Forecast, 2000-2005 

Exhibit 2-15:  2000, Volumetric Pump Products Market, Share by Supplier 

Exhibit 2-16:  2001, Selected Syringe Pumps 

Exhibit 2-17:  Syringe Pump Products, Market Forecast, 2000-2005 

Exhibit 2-18:  2000, Syringe Pumps Market, Share by Supplier 

Exhibit 2-19:  2001, Selected Ambulatory Pumps 

Exhibit 2-20:  Ambulatory Pump Products, Market Forecast, 2000-2005 

Exhibit 2-21:  2000, Ambulatory Pumps Market, Share by Supplier 

Exhibit 2-22:  2001, Selected Disposable Infusion Pumps 

Exhibit 2-23:  Disposable Infusion Pumps, Market Forecast, 2000-2005 

Exhibit 2-24:  2000, Disposable Infusion Pumps Market, Share by Supplier 

Exhibit 2-25:  2001, Selected Implantable Infusion Pumps 

Exhibit 2-26:  Implantable Infusion Pumps, Market Forecast, 2000-2005 

Exhibit 2-27:  2000, Implantable Infusion Pumps Market, Share by Supplier 

Exhibit 2-28:  2001, Selected External Insulin Pumps 

Exhibit 2-29:  External Insulin Pump Products, Market Forecast, 2000-2005 

Exhibit 2-30:  2000, External Insulin Pump Products Market, Share by Supplier 

Exhibit 2-31:  2001, Selected Enteral Nutrition Pumps 

Exhibit 2-32:  Enteral Nutrition Pumps and Disposable Products, Market Forecast, 2000-2005 

Exhibit 2-33:  2000, Enteral Nutrition Pumps and Disposable Products Market, Share by Supplier 

Exhibit 2-34:  Intravenous Gravity Infusion Systems, Market Forecast, 2000-2005 

Exhibit 2-35:  2000, Intravenous Gravity Infusion Systems Market, Share by Supplier 

Exhibit 2-36:  2001, Selected Vascular Catheters and Implantable Ports 

Exhibit 2-37:  Vascular Catheters and Implantable Ports, Market Forecast, 2000-2005 

Exhibit 2-38:  Short Peripheral Catheters, Market Forecast, 2000-2005 

Exhibit 2-39:  2000, Short Peripheral Catheters Market, Share by Supplier 

Exhibit 2-40:  Midline Catheters, Market Forecast, 2000-2005 

Exhibit 2-41:  2000, Midline Catheters Market, Share by Supplier 

Exhibit 2-42:  Peripherally Inserted Central Catheters, Market Forecast, 2000-2005 

Exhibit 2-43:  2000, Peripherally Inserted Central Catheters Market, Share by Supplier 

Exhibit 2-44:  Central Venous Catheters, Market Forecast, 2000-2005 

Exhibit 2-45:  2000, Central Venous Catheters Market, Share by Supplier 

Exhibit 2-46:  Implantable Ports, Market Forecast, 2000-2005 

Exhibit 2-47:  2000, Implantable Ports Market, Share by Supplier 

 

Exhibit 3-1:    Transdermal Patch Products, Market Forecast, 2000-2005 

Exhibit 3-2:    2001, Selected Nitroglycerin and Clonidine Transdermal Patch Products 

Exhibit 3-3:    Nitroglycerin and Clonidine Patch Products, Market Forecast, 2000-2005 

Exhibit 3-4:    2000, Nitroglycerin Patch Products Market, Share by Supplier 

Exhibit 3-5:    2001, Selected Estrogen Patch Products 

Exhibit 3-6:    Estrogen Replacement Therapy Products, Market Forecast, 2000-2005 

Exhibit 3-7:    2000, Estrogen Patch Products Market, Share by Supplier 

Exhibit 3-8:    2001, Selected Nicotine Patch Products 

Exhibit 3-9:    Nicotine Replacement Therapy Patch and Gum Products, Market Forecast, 2000-2005 

Exhibit 3-10:  2000, Nicotine Replacement Therapy Patch Products Market, Share by Supplier 

Exhibit 3-11:  2001, Selected Analgesic Patch Products 

Exhibit 3-12:  Analgesic Patch Products, Market Forecast, 2000-2005 

Exhibit 3-13:  2000, Analgesic Patch Products Market, Share by Supplier 

 

Exhibit 4-1:    Prevalence of Chronic Obstructive Respiratory Disorders, 2000 and 2005 

Exhibit 4-2:    2001, Selected Inhalation Therapy Agents for the Treatment of Chronic Obstructive Respiratory Disorders 

Exhibit 4-3:    2001, Comparative Analysis of Inhalation Drug-Delivery Systems 

Exhibit 4-4:    2001, Selected Dry-Powder Inhaler- and Metered-Dose Inhaler-Based Drugs for Chronic Obstructive Respiratory Disorder Indications 

Exhibit 4-5:    Dry-Powder and Metered-Dose Inhalers for the Treatment of Chronic Obstructive Respiratory Disorders, and Insulin Delivery Systems, Market Forecast, 2000-2005 

Exhibit 4-6:    Dry-Powder and Metered-Dose Inhalers for the Treatment of Chronic Obstructive Respiratory Disorders, Market Forecast, by Drug Type, 2000-2005 

Exhibit 4-7:    Inhaled Insulin Products, Market Forecast, 2002-2005 

Exhibit 4-8:    2000, Dry-Powder and Metered-Dose Inhalers for the Treatment of Chronic Obstructive Respiratory Disorders, Share by Supplier 



COMPANIES COVERED:

  1. Abbott Laboratories
  2. Alaris Medical Systems, Inc.
  3. Arrow International, Inc.
  4. Aventis Pharma/Aventis Group
  5. C.R. Bard, Inc.
  6. Baxter Healthcare Corporation/Baxter International
  7. Becton Dickinson and Company
  8. Bioject Medical Technologies, Inc.
  9. Boehringer Ingelheim Pharmaceuticals, Inc.
  10. /Boehringer Ingelheim Group
  11. Disetronic Medical Systems, Inc./Disetronic Group
  12. /Disetronic Holding AG
  13. Endo Pharmaceuticals, Inc.
  14. Johnson & Johnson
  15. GlaxoSmithKline
  16. Horizon Medical Products, Inc.
  17. I-Flow Corporation
  18. Kendall Healthcare Products Corporation/Tyco
  19. International LTD
  20. Medex/Saint-Gobain Performance Plastics/Saint-Gobain Group
  21. Medtronic, Inc.
  22. MiniMed, Inc.
  23. Novartis Pharmaceuticals Corporation/Novartis AG
  24. Novo Nordisk Pharmaceuticals, Inc./Novo Nordisk AS
  25. Schering-Plough Corporation
  26. SIMS Deltec, Inc./Smith Industries Medical Systems/Smiths Group PLC
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