GLOBAL NEUROSTIMULATION DEVICES MARKET

313 Pages | 63 Exhibits | 2016 Analysis | Forecasts Through 2020

OVERVIEW:
This analysis includes a discussion of products, current/forecast markets, competitors, and opportunities in the global neurostimulation devices market for more than 20 existing and emerging therapy areas.

NEUROSTIMULATION MARKET HIGHLIGHTS

  • The dynamic global neurostimulation devices market was valued at more than $3.9 billion in 2015 and is expected to grow at a healthy CAGR of 8.4% over the forecast period. The U.S. contributed the majority of sales, although the ROW share is climbing.
  • Spinal cord stimulation (SCS), cochlear implants and deep brain stimulation (DBS) led the global market in 2015.
  • Competition has been fierce, shifting market shares and increasing competitive pressure. Market leaders are struggling to stay ahead of core competition as well as dozens of new startups developing new, improved technologies improving therapy and outcomes. Less invasive technology is becoming more mainstream.
  • Demographic trends, the strong desire for non-drug alternatives (especially for chronic pain management), and strong innovation are among several factors spurring market growth despite a difficult economy.
KEY QUESTIONS ANSWERED
  • What are the key drivers and limiters to the Global Neurostimulation Devices Market?
  • Which competitors are leading the market and introducing new technology?
  • How are technological advancements impacting market growth?
  • Which areas of the neurostimulation devices market are experiencing dynamic growth?
  • What are future growth strategies of leading and emerging competitors?


TABLE OF CONTENTS:
EXECUTIVE SUMMARY
 
i. Global Implantable Neurostimulation Devices Market 
ii. Methodology 

Exhibit ES-1: Estimated U.S. and Global Prevalence of Selected Neurological Conditions 
Exhibit ES-2: 2015, Global Implantable Neurostimulation Devices Market, Share by U.S. and ROW 
Exhibit ES-3: 2015, Global Implantable Neurostimulation Devices Market, Estimated Percentage of Sales, by Type of Therapy 
Exhibit ES-4: 2016, Leading Competitors and Products in the Global Implantable Neurostimulation Devices Market 

1. NEUROSTIMULATION TECHNOLOGIES OVERVIEW
 
1.1 Implantable Neurostimulators 
	1.1.1 Deep Brain Stimulators 
	1.1.2 Gastric Nerve Stimulators 
	1.1.3 Sacral Nerve Stimulators 
	1.1.4 Spinal Cord Stimulators 
	1.1.5 Vagus Nerve Stimulators 
	1.1.6 Vagal Blocking for Obesity 
	1.1.7 Cochlear Implants 
	1.1.8 Retinal Implants 
1.2 Noninvasive Peripheral Nerve Stimulation 
1.3 Transcutaneous Electrical Nerve Stimulation 
1.4 Closed-Loop Stimulation 
1.5 Hypoglossal Nerve Stimulation 
1.6 Transcutaneous Magnetic Stimulation 
1.7 External Trigeminal Nerve Stimulation 

Exhibit 1-1: Estimated U.S. and Global Prevalence of Selected Neurological Conditions 
Exhibit 1-2: Selected Advantages and Disadvantages of Neurostimulation Therapy 
Exhibit 1-3: Estimated Number of Neurostimulation Implants Implanted, Worldwide, by Selected Neurological Condition 
Exhibit 1-4: Schematic Illustration of Deep Brain Stimulation  

2. NEUROSTIMULATION DEVICES AND COMPETITORS
 
	2.1.1 Alzheimer's Disease 
		2.1.1.1 Beijing Pins Medical Co., Ltd. 
		2.1.1.2 The Magstim Company 
		2.1.1.3 Functional Neuromodulation Ltd. 
	2.1.2 Attention-Deficit/Hyperactivity Disorder 
		2.1.2.1 Brainsway 
		2.1.2.2 NeuroSigma 
	2.1.3 Autism 
		2.1.3.1 Brainsway 
		2.1.3.2 MagVenture A/S 
	2.1.4 Blindness 
		2.1.4.1 Bionic Vision Australia 
		2.1.4.2 Pixium Vision 
		2.1.4.3 Retina Implant AG 
		2.1.4.4 Second Sight Medical Products 
	2.1.5 Chronic Depression
		2.1.5.1 Brainsway Ltd. 
		2.1.5.2 LivaNova (Cyberonics/Sorin Group) 
		2.1.5.3 Fisher Wallace 
		2.1.5.4 MagVenture A/S 
		2.1.5.5 Medtronic
		2.1.5.6 Neuronetics 
		2.1.5.7 NeuroSigma 
		2.1.5.8 St. Jude Medical 
	2.1.6 Chronic Heart Failure 
		2.1.6.1 BioControl Medical 
		2.1.6.2 LivaNova plc (previously Cyberonics/ Sorin Group) 
		2.1.6.3 Medtronic
		2.1.6.4 St. Jude Medical 
	2.1.7 Chronic Migraine Headache 
		2.1.7.1 Boston Scientific 
		2.1.7.2 Medtronic
		2.1.7.3 St. Jude Medical 
		2.1.7.4 Others (Cluster Headache/Migraine) 
			2.1.7.4.1 Autonomic Technologies, Inc. 
			2.1.7.4.2 ElectroCore, LLC 
	2.1.8 Chronic Pain 
		2.1.8.1 Boston Scientific 
		2.1.8.2 Medtronic
		2.1.8.3 St. Jude Medical 
			2.1.8.3.1 Neurotherm/St. Jude Medical 
		2.1.8.4 Others 
			2.1.8.4.1 Bioness, Inc. 
			2.1.8.4.2 Mainstay Medical 
			2.1.8.4.3 NeuroMetrix 
			2.1.8.4.4 Neuros Medical 
			2.1.8.4.5 Nevro Corp.
				2.1.8.4.5.1 SENZA-RCT Trial 
			2.1.8.4.6 Nuvectra Corporation 
			2.1.8.4.7 Saluda Medical 
			2.1.8.4.8 SPR Therapeutics 
			2.1.8.4.9 Stimwave, LLC 
	2.1.9 Dystonia, Essential Tremor, and Parkinson's Disease 
		2.1.9.1 Boston Scientific 
		2.1.9.2 Medtronic
		2.1.9.3 St. Jude Medical 
		2.1.9.4 Aleva Therapeutics (and Nuvectra) 
	2.1.10 Epilepsy 
		2.1.10.1 Beijing Pins Medical Co., Ltd 
		2.1.10.2 Cerbomed GmbH 
		2.1.10.3 CerebralRx/BioControl Medical 
		2.1.10.4 LivaNova plc (previously Cyberonics/Sorin Group) 
		2.1.10.5 Electrical Geodesics, Inc. 
		2.1.10.6 Medtronic plc 
		2.1.10.7 NeuroPace 
		2.1.10.8 NeuroSigma 
		2.1.10.9 NeuroVista/Cyberonics 
	2.1.11 Foot Drop 
		2.1.11.1 Bioness, Inc. 
	2.1.12 Gastro-Esophageal Reflux Disease
		2.1.12.1 EndoStim 
	2.1.13 Gastroparesis 
		2.1.13.1 Medtronic
	2.1.14 Hearing Loss 
		2.1.14.1 Advanced Bionics AG/Sonova Holding AG 
		2.1.14.2 Cochlear, Ltd. 
		2.1.14.3 MED-EL 
	2.1.15 Incontinence 
		2.1.15.1 Medtronic
			2.1.15.1.1 NURO System 
		2.1.15.2 Bioness, Inc. 
		2.1.15.3 Cogentix Medical (Uroplasty/Vision-Sciences) 
		2.1.15.4 Nuvectra Corporation 
	2.1.16 Obesity/Diabesity 
		2.1.16.1 EnteroMedics 
		2.1.16.2 MetaCure
	2.1.17 Obsessive-Compulsive Disorder 
		2.1.17.1 Medtronic
	2.1.18 Sleep Apnea 
		2.1.18.1 ImThera Medical 
		2.1.18.2 Inspire Medical Systems
		2.1.18.3 Respicardia/LivaNova 
		2.1.18.4 Others 
	2.1.19 Spinal Cord Injury/Paralysis 
		2.1.19.1 BrainGate Research Team 
		2.1.19.2 Synapse Biomedical 
	2.1.20 Stroke 
		2.1.20.1 MicroTransponder 
	2.1.21 Tinnitus 
		2.1.21.1 Brainsway 
		2.1.21.2 Medtronic
		2.1.21.3 MicroTransponder 

Exhibit 2-1: Functional Neuromodulation's DBS-f Technology and Early Clinical Results 
Exhibit 2-2: NeuroSigma's Monarch eTNS system 
Exhibit 2-3: MagVenture's MagPro100x System Utilized in Repetitive Transcranial Magnetic Stimulation
Exhibit 2-4: Bionic Vision Australia's Retinal Stimulation Technology 
Exhibit 2-5: Pixium Vision's Bio-Mimetic Camera 
Exhibit 2-6: Retina Implant's Subretinal Implant Technology 
Exhibit 2-7: Second Sight Medical Product's Argus II Retinal Prosthesis System 
Exhibit 2-8: The Fisher Wallace Stimulator
Exhibit 2-9: MagVenture's MagVita TMS Therapy system for the Treatment of Depression 
Exhibit 2-10: Neuronetic's NeuroStar TMS Therapy System for the Treatment of Depression 
Exhibit 2-11: BioControl Medical's CardioFit Stimulator 
Exhibit 2-12: Autonomic Technologies' ATI (Pulsante) Neurostimulation System 
Exhibit 2-13: ElectroCore's Self-Administered gammaCore nVNS System for Treatment of Chronic Cluster Headache and Migraine 
Exhibit 2-14: Boston Scientific's Precision Spectra SCS System and Precision Plus SCS System 
Exhibit 2-15: Medtronic's RestoreSensor with SureScan MRI Technology for the Treatment of Chronic Pain 
Exhibit 2-16: St. Jude Medical's New Proclaim Elite Recharge-Free SCS System and Prodigy SCS System 
Exhibit 2-17: St. Jude Medical's Radiofrequency Ablation Technology Application to the Facet Joint in the Spine 
Exhibit 2-18: NeuroMetrix's SENSUS Pain Management System for the Treatment of Chronic Intractable Pain 
Exhibit 2-19: NeuroMetrix's New Non-Prescription Quell Wearable Pain Relief Technology 
Exhibit 2-20: Neuros Medical's Altius System High Frequency Nerve Block Technology for the Treatment of Chronic, Peripheral Pain 
Exhibit 2-21: Nevro's Senza SCS System 
Exhibit 2-22: Nuvectra's Algovita SCS System 
Exhibit 2-23: SPR Therapeutic's Smartpatch PNS System for the Treatment
of Chronic Shoulder Pain 
Exhibit 2-24: Stimwave Technologies' FREEDOM SCS System Wireless Pain Relief Technology 
Exhibit 2-25: Medtronic's Activa Neurostimulator for the Treatment of Parkinson's Disease and Essential Tremor 
Exhibit 2-26: St. Jude Medical's New Infinity DBS Primary Cell IPG for the Treatment of Parkinson's Disease, Essential Tremor and Dystonia 
Exhibit 2-27: Cerbomed's Noninvasive NEMOS t-VNS Device for Treatment of Refractory Epilepsy 
Exhibit 2-28: LivaNova's VNS Therapy Systems for the Treatment of Epilepsy 
Exhibit 2-29: NeuroPace's RNS/Responsive Neurostimulation for the Suppression of Epileptic Seizures 
Exhibit 2-30: NeuroVista/Cyberonic's Seizure Advisory System for the Prediction of Epileptic Seizures 
Exhibit 2-31: Bioness' L300 Foot Drop FES System 
Exhibit 2-32: The Enterra II Gastric Neurostimulator for the Treatment of Gastroparesis 
Exhibit 2-33: Advanced Bionic's HiRes 90K Implant System for the Treatment of Hearing Loss 
Exhibit 2-34: Cochlear Ltd.'s Nucleus 6 Sound Processor and Function of Cochlear Implant System 
Exhibit 2-35: MED-EL's MAESTRO and SYNCHRONY Cochlear Implant Systems 
Exhibit 2-36: Medtronic's InterStim II Therapy System for the Treatment of Incontinence 
Exhibit 2-37: Medtronic's Office-Based NURO System for Percutaneous Tibial Neuromodulation (PTNM) Treatment of OAB 
Exhibit 2-38: Cogentix Medical's Urgent PC System for the Treatment of Overactive Bladder 
Exhibit 2-39: EnteroMedics' Maestro System 
Exhibit 2-40: Overview of EnteroMedics' vBloc Therapy and Vagus Nerve Function 
Exhibit 2-41: Potential Benefits and Risks of vBloc Therapy 
Exhibit 2-42: Comparison of vBloc Therapy, Laparoscopic Banding, and Gastric Bypass 
Exhibit 2-43: MetaCure's DIAMOND (TANTALUS) Gastric Stimulation System 
Exhibit 2-44: The aura6000 System for the Treatment of Obstructive Sleep Apnea2- 
Exhibit 2-45: Inspire Medical System's Inspire II System for the Treatment of Obstructive Sleep Apnea 
Exhibit 2-46: An Illustration of Normal and Abnormal Breathing Patterns in Patients with Central Sleep Apnea 
Exhibit 2-47: Synapse Biomedical's NeuRx Diaphragm Pacing System 
Exhibit 2-48: MicroTransponder's Serenity System for the Treatment of Tinnitus 

3. IMPLANTABLE NEUROSTIMULATION DEVICES MARKET
 
3.1 Market Forecast 
3.2 Competitive Analysis 
	3.2.1 Market Share 
		3.2.1.1 Market Share, Global 
		3.2.1.2 Market Share, U.S. 
		3.2.1.3 Market Share, ROW 
	3.2.2 Detailed Analysis, by Lead Competitor 
		3.2.2.1 Medtronic plc 
		3.2.2.2 Boston Scientific 
		3.2.2.3 St. Jude Medical 
		3.2.2.4 LivaNova 
		3.2.2.5 Nevro Corp. 
		3.2.2.6 Stimwave 
3.3 Leading Neurostimulation Products by Company, Indication 

Exhibit 3-1: Implantable Neurostimulation Devices, Global Market Forecast, 2015-2020 
Exhibit 3-2: Selected Market Drivers and Limiters for Implantable Neurostimulation Devices 
Exhibit 3-3: 2015, Global Implantable Neurostimulation Devices Market, Share by Supplier  
Exhibit 3-4: 2015, U.S. Implantable Neurostimulation Devices Market, Share by Supplier 
Exhibit 3-5: 2015, ROW Implantable Neurostimulation Devices Market, Share by Supplier 
Exhibit 3-6: 2015, Global Implantable Neurostimulation Devices Market (DBS/GNS/SCS/SNS/VNS Only), Share by Supplier 
Exhibit 3-7: 2016, Leading Competitors and Products in the Implantable Neurostimulation Devices Market 

APPENDIX A: COMPANY LISTING

APPENDIX B: BIBLIOGRAPHY



COMPANIES COVERED:

  1. Abbott
  2. Advanced Bionics Corporation/Sonova Holdings
  3. Aleva Neurotherapeutics SA
  4. Autonomic Technologies, Inc.
  5. BioControl Medical, Inc.
  6. Bioness, Inc.
  7. Bionic Vision Australia
  8. Boston Scientific Corporation
  9. BrainGate Research Team
  10. Brainsway Ltd.
  11. Cerbomed GmbH
  12. CerebralRX/BioControl Medical LTD
  13. Cochlear, LTD
  14. Cogentix Medical
  15. Cyberonics, Inc./LivaNova PLC
  16. Electrical Geodesics, Inc.
  17. ElectroCore, LLC
  18. EndoStim
  19. EnteroMedics, Inc.
  20. Fisher Wallace
  21. Functional Neuromodulation, Ltd.
  22. Greatbatch Medical
  23. ImThera Medical, Inc.
  24. Inspire Medical Systems, Inc.
  25. LivaNova PLC
  26. The Magstim Company LTD
  27. MagVenture A/S
  28. Mainstay Medical
  29. MED-EL Corporation
  30. Medtronic plc
  31. MetaCure LTD
  32. MicroTransponder, Inc.
  33. NeuroMetrix, Inc.
  34. Neuronetics, Inc.
  35. NeuroPace, Inc.
  36. Neuros Medical, Inc.
  37. NeuroSigma, Inc.
  38. Nevro Corp.
  39. Nuvectra Corporation
  40. Pixium Vision
  41. Respicardia, Inc.
  42. Retina Implant AG
  43. Saluda Medical
  44. Second Sight Medical Products, Inc.
  45. SPR Therapeutics LLC
  46. St. Jude Medical, Inc.
  47. Stimwave Technologies, Incorporated
  48. Synapse Biomedical, Inc.
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