SPAIN DISEASE INCIDENCE AND PREVALENCE

339 Pages | 97 Exhibits | 2012 Analysis

OVERVIEW:
As the aging population in Europe increases and the average life span lengthens, the incidence and prevalence of major diseases/disorders are expected to significantly impact the European healthcare industry. This dynamic new report from Medtech Insight examines the incidence and prevalence of selected diseases/disorders in Spain and compares them with those of the Benelux countries (Belgium, Luxembourg, and the Netherlands), the Nordic countries (Denmark, Finland, Norway, and Sweden), and the European Union (Austria, Belgium, Bulgaria, Cyprus, the Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, and the United Kingdom).

This report is the fourth in a series of five reports (Disease Incidence and Prevalence for France, Germany, Italy, Spain, and the United Kingdom) that examine the etiology and epidemiology of the most prevalent and costly diseases/disorders in Europe. Topics covered by each of these reports include Alzheimer's disease, anemia, arthritis, asthma, benign prostatic hyperplasia, bronchitis, burns/traumatic wounds, cancer, depression, diabetes, emphysema, erectile dysfunction, glaucoma, heart failure, human immunodeficiency virus/acquired immune deficiency syndrome, hypertension, infertility, multiple sclerosis, osteoporosis, pneumonia, stroke, and transmissible spongiform encephalopathies, among others.

In addition to proprietary data utilized from Medtech Insight's internal resources, many agencies and organizations have provided information including Alzheimer's Disease International, Cystic Fibrosis Europe, European Association of Urology, European Cancer Observatory, European Centre for Disease Prevention and Control, European Kidney Health Alliance, European Society of Cardiology, International Diabetes Federation, International Osteoporosis Foundation, Multiple Sclerosis International Federation, Organization for Economic Cooperation and Development, Spanish Association for the Fight against Hemoglobinopathies and Thalassemias (Asociacion Espanola de Lucha contra las Hemoglobinopatias y Talasemias), Spanish Federation against Cystic Fibrosis (Federacion Espanola contra la Fibrosis Quistica), Spanish Hemophilia Society (Federacion Espanola de Hemofilia), Spanish Society of Sleep (Sociedad Espanola del Sueno), and the World Health Organization, among others.

TABLE OF CONTENTS:
INTRODUCTION

1. EUROPEAN HEALTHCARE OVERVIEW

1.1 Healthcare Spending 
1.2 Healthcare Facilities and Providers 
1.3 Reimbursement Structures and Common Market Directives 
1.4 Selected National Healthcare Profiles for Spain 
	1.4.1 Healthcare Organization and Reform 
	1.4.2 Hospital/Medical Services and Reimbursement 

Exhibit 1-1: European Healthcare Expenditures as a Percentage of Gross Domestic Product, Selected Countries, 2002-2008 
Exhibit 1-2: European Union Population Statistics Comparison for the Years 2000, 2010, and 2020 
Exhibit 1-3: Classification of European Healthcare Providers 
Exhibit 1-4: Healthcare Providers within the European Economy 
Exhibit 1-5: Average Hospital Length of Stay, Acute Care, Selected Countries, 2002-2008 
Exhibit 1-6: European Union, Medical Devices Risk Classification System 
Exhibit 1-7: Spain, Selected National Healthcare Statistics 

2. BLOOD DISORDERS:  ANEMIA AND HEMOPHILIA

2.1 Anemia 
	2.1.1 Iron Deficiency Anemia 
		2.1.1.1 Etiology 
		2.1.1.2 Epidemiology 
	2.1.2 Sickle Cell Anemia 
		2.1.2.1 Etiology 
		2.1.2.2 Epidemiology 
	2.1.3 Thalassemia 
		2.1.3.1 Etiology 
		2.1.3.2 Epidemiology 
2.2 Hemophilia 
	2.2.1 Etiology 
	2.2.2 Epidemiology 

Exhibit 2-1: Europe, Estimated Prevalence of Anemia, by Age and Gender 
Exhibit 2-2: Spain and Europe, Iron Deficiency Anemia, Comparative Incidence and Prevalence 
Exhibit 2-3: Spain and Europe, Sickle Cell Anemia, Comparative Incidence and Prevalence 
Exhibit 2-4: Spain and Europe, Thalassemia, Comparative Prevalence 
Exhibit 2-5: Spain and Europe, Hemophilia, Comparative Incidence and Prevalence 

3. CANCER

3.1 Bladder Cancer 
	3.1.1 Etiology 
	3.1.2 Epidemiology 
3.2 Brain Tumors 
	3.2.1 Etiology 
	3.2.2 Epidemiology 
3.3 Breast Cancer 
	3.3.1 Etiology 
	3.3.2 Epidemiology 
3.4 Cervical/Uterine Cancer 
	3.4.1 Etiology 
	3.4.2 Epidemiology 
3.5 Colon/Rectal Cancer 
	3.5.1 Etiology 
	3.5.2 Epidemiology 
3.6 Esophageal Cancer 
	3.6.1 Etiology 
	3.6.2 Epidemiology 
3.7 Kidney/Urothelial Cancer 
	3.7.1 Etiology 
	3.7.2 Epidemiology 
3.8 Leukemia 
	3.8.1 Etiology 
	3.8.2 Epidemiology 
3.9 Lung Cancer 
	3.9.1 Etiology 
	3.9.2 Epidemiology 
3.10 Lymphoma 
	3.10.1 Etiology 
	3.10.2 Epidemiology 
3.11 Melanoma 
	3.11.1 Etiology 
	3.11.2 Epidemiology 
3.12 Oral Cancer 
	3.12.1 Etiology 
	3.12.2 Epidemiology 
3.13 Ovarian Cancer 
	3.13.1 Etiology 
	3.13.2 Epidemiology 
3.14 Pancreatic Cancer 
	3.14.1 Etiology 
	3.14.2 Epidemiology 
3.15 Prostate Cancer 
	3.15.1 Etiology 
	3.15.2 Epidemiology 
3.16 Stomach Cancer 
	3.16.1 Etiology 
	3.16.2 Epidemiology 
3.17 Testicular Cancer 
	3.17.1 Etiology 
	3.17.2 Epidemiology 

Exhibit 3-1: Spain and Europe, Bladder Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-2: Spain and Europe, Brain Tumors, Comparative Incidence, by Gender 
Exhibit 3-3: Spain and Europe, Breast Cancer, Comparative Incidence and Mortality 
Exhibit 3-4: Spain and Europe, Cervical/Uterine Cancer, Comparative Incidence and Mortality 
Exhibit 3-5: Spain and Europe, Colon/Rectal Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-6: Spain and Europe, Esophageal Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-7: Spain and Europe, Kidney/Urothelial Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-8: Spain and Europe, Leukemia, Comparative Incidence and Mortality, by Gender 
Exhibit 3-9: Spain and Europe, Lung Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-10: Spain and Europe, Lymphoma, Comparative Incidence and Mortality, by Gender 
Exhibit 3-11: Spain and Europe, Melanoma, Comparative Incidence and Mortality, by Gender 
Exhibit 3-12: Spain and Europe, Oral Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-13: Spain and Europe, Ovarian Cancer, Comparative Incidence and Mortality 
Exhibit 3-14: Spain and Europe, Pancreatic Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-15: Spain and Europe, Prostate Cancer, Comparative Incidence and Mortality 
Exhibit 3-16: Spain and Europe, Stomach Cancer, Comparative Incidence and Mortality, by Gender 
Exhibit 3-17: Spain and Europe, Testicular Cancer, Comparative Incidence and Mortality 

4. CARDIOVASCULAR DISORDERS

4.1 Cardiac Arrhythmia 
	4.1.1 Etiology 
	4.1.2 Epidemiology 
4.2 Heart Failure 
	4.2.1 Etiology 
	4.2.2 Epidemiology 
4.3 Heart Valve Disorders 
	4.3.1 Etiology 
	4.3.2 Epidemiology 
4.4 Hypertension 
	4.4.1 Etiology 
	4.4.2 Epidemiology 
4.5 Vascular Disorders 
	4.5.1 Aneurysms 
		4.5.1.1 Etiology 
		4.5.1.2 Epidemiology 
	4.5.2 Angina Pectoris 
		4.5.2.1 Etiology 
		4.5.2.2 Epidemiology 
	4.5.3 Atherosclerosis 
		4.5.3.1 Etiology 
		4.5.3.2 Epidemiology 
	4.5.4 Myocardial Infarction 
		4.5.4.1 Etiology 
		4.5.4.2 Epidemiology 
	4.5.5 Peripheral Vascular Disease 
		4.5.5.1 Etiology 
		4.5.5.2 Epidemiology 

Exhibit 4-1: Spain and Europe, Atrial Fibrillation, Comparative Incidence and Prevalence 
Exhibit 4-2: Spain and Europe, Atrial Flutter, Comparative Incidence and Prevalence 
Exhibit 4-3: Spain and Europe, Supraventricular Tachycardia, Comparative Incidence and Prevalence 
Exhibit 4-4: Spain and Europe, Heart Failure, Comparative Incidence and Prevalence, by Gender 
Exhibit 4-5: Spain and Europe, Heart Valve Disorders, Comparative Incidence and Prevalence, by Gender 
Exhibit 4-6: Spain and Europe, Hypertension, Comparative Incidence and Prevalence 
Exhibit 4-7: Spain and Europe, Aneurysms, Comparative Incidence and Prevalence 
Exhibit 4-8: Standard Angina Pectoris Classification 4-33
Exhibit 4-9: Spain and Europe, Angina Pectoris, Comparative Incidence and Prevalence, by Gender 
Exhibit 4-10: Spain and Europe, Hypercholesteremia, Comparative Prevalence, by Gender and Selected Country 
Exhibit 4-11: Spain and Europe, Myocardial Infarction, Comparative Incidence and Prevalence, by Gender 
Exhibit 4-12: Spain and Europe, Peripheral Vascular Disease, Comparative Incidence and Prevalence 

5. METABOLIC DISORDERS

5.1 Cholelithiasis 
	5.1.1 Etiology 
	5.1.2 Epidemiology 
5.2 Chronic Kidney Disease/End-Stage Renal Disease 
	5.2.1 Etiology 
	5.2.2 Epidemiology 
5.3 Diabetes 
	5.3.1 Etiology 
	5.3.2 Epidemiology 
5.4 Urolithiasis 
	5.4.1 Etiology 
	5.4.2 Epidemiology 

Exhibit 5-1: Spain and Europe, Cholelithiasis, Comparative Incidence and Prevalence 
Exhibit 5-2: Spain and Europe, Chronic Kidney Disease, Comparative Incidence and Prevalence, by Gender 
Exhibit 5-3: Spain and Europe, Diabetes, Comparative Incidence, by Gender 
Exhibit 5-4: Spain and Europe, Diabetes, Comparative Prevalence, by Share of Population 
Exhibit 5-5: Spain and Europe, Diabetes, Comparative Prevalence, by Gender and Age Group 
Exhibit 5-6: Spain and Europe, Urolithiasis, Comparative Incidence and Prevalence 

6. MUSCULOSKELETAL DISORDERS

6.1 Arthritis 
	6.1.1 Etiology 
	6.1.2 Epidemiology 
6.2 Carpal Tunnel Syndrome 
	6.2.1 Etiology 
	6.2.2 Epidemiology 
6.3 Meniscal and Ligament/Tendon Injuries 
	6.3.1 Etiology 
	6.3.2 Epidemiology 
6.4 Duchenne Muscular Dystrophy 
	6.4.1 Etiology 
	6.4.2 Epidemiology 
6.5 Osteoporosis 
	6.5.1 Etiology 
	6.5.2 Epidemiology 

Exhibit 6-1: Spain and Europe, Rheumatoid Arthritis, Comparative Incidence and Prevalence 
Exhibit 6-2: Spain and Europe, Osteoarthritis of the Knee, Comparative Incidence and Prevalence 
Exhibit 6-3: Spain and Europe, Osteoarthritis of the Hip, Comparative Incidence and Prevalence 
Exhibit 6-4: Spain and Europe, Carpal Tunnel Syndrome, Comparative Incidence and Prevalence 
Exhibit 6-5: Spain and Europe, Meniscal and Ligament/Tendon Injuries of the Knee, Comparative Incidence and Prevalence 
Exhibit 6-6: Spain and Europe, Duchenne Muscular Dystrophy, Comparative Incidence and Prevalence 
Exhibit 6-7: Spain and Europe, Osteoporosis, Comparative Incidence and Prevalence 

7. NEUROLOGIC AND PSYCHIATRIC DISORDERS

7.1 Alzheimer's Disease and Dementia 
	7.1.1 Etiology 
	7.1.2 Epidemiology 
7.2 Amyotrophic Lateral Sclerosis 
	7.2.1 Etiology 
	7.2.2 Epidemiology 
7.3 Bipolar Disorder 
	7.3.1 Etiology 
	7.3.2 Epidemiology 
7.4 Cerebrovascular Disorders 
	7.4.1 Arteriovenous Malformation 
		7.4.1.1 Etiology 
		7.4.1.2 Epidemiology 
	7.4.2 Stroke 
		7.4.2.1 Etiology 
		7.4.2.2 Epidemiology 
7.5 Depression 
	7.5.1 Etiology 
	7.5.2 Epidemiology 
7.6 Epilepsy 
	7.6.1 Etiology 
	7.6.2 Epidemiology
7.7 Huntington's Disease 
	7.7.1 Etiology 
	7.7.2 Epidemiology 
7.8 Hydrocephalus 
	7.8.1 Etiology 
	7.8.2 Epidemiology 
7.9 Multiple Sclerosis 
	7.9.1 Etiology 
	7.9.2 Epidemiology 
7.10 Myasthenia Gravis 
	7.10.1 Etiology 
	7.10.2 Epidemiology 
7.11 Parkinson's Disease 
	7.11.1 Etiology 
	7.11.2 Epidemiology 
7.12 Schizophrenia 
	7.12.1 Etiology 
	7.12.2 Epidemiology 

Exhibit 7-1: 2010, Europe, Diagnosed and Undiagnosed Dementia, Incidence Rates, by Age and Gender 
Exhibit 7-2: 2010, Europe, Diagnosed and Undiagnosed Dementia, Prevalence Rates, by Age and Gender 
Exhibit 7-3: Spain and Europe, Alzheimer's Disease, Comparative Incidence and Prevalence 
Exhibit 7-4: Spain and Europe, Amyotrophic Lateral Sclerosis, Comparative Incidence and Prevalence 
Exhibit 7-5: Spain and Europe, Bipolar Disorder, Comparative Incidence and Prevalence 
Exhibit 7-6: Spain and Europe, Arteriovenous Malformation, Comparative Incidence and Prevalence 
Exhibit 7-7: Spain and Europe, Stroke, Comparative Incidence and Prevalence 
Exhibit 7-8: Spain and Europe, Depression, Comparative Prevalence 
Exhibit 7-9: Spain and Europe, Epilepsy, Comparative Incidence and Prevalence 
Exhibit 7-10: Spain and Europe, Huntington's Disease, Comparative Incidence and Prevalence 
Exhibit 7-11: Spain and Europe, Hydrocephalus, Comparative Incidence and Prevalence 
Exhibit 7-12: Spain and Europe, Multiple Sclerosis, Comparative Incidence and Prevalence 
Exhibit 7-13: Spain and Europe, Myasthenia Gravis, Comparative Incidence and Prevalence 
Exhibit 7-14: Spain and Europe, Parkinson's Disease, Comparative Incidence and Prevalence 
Exhibit 7-15: Spain and Europe, Schizophrenia, Comparative Incidence and Prevalence 

8. OPHTHALMIC DISORDERS:  CATARACTS AND GLAUCOMA

8.1 Cataracts 
	8.1.1 Etiology 
	8.1.2 Epidemiology 
8.2 Glaucoma 
	8.2.1 Etiology 
	8.2.2 Epidemiology

Exhibit 8-1: Spain and Europe, Cataracts, Comparative Incidence and Prevalence
Exhibit 8-2: Spain and Europe, Glaucoma, Comparative Incidence and Prevalence 

9. REPRODUCTIVE AND GENITOURINARY DISORDERS

9.1 Benign Prostatic Hyperplasia 
	9.1.1 Etiology 
	9.1.2 Epidemiology 
9.2 Endometriosis 
	9.2.1 Etiology 
	9.2.2 Epidemiology 
9.3 Erectile Dysfunction 
	9.3.1 Etiology 
	9.3.2 Epidemiology 
9.4 Infertility 
	9.4.1 Etiology 
	9.4.2 Epidemiology 
9.5 Urinary Incontinence 
	9.5.1 Etiology 
	9.5.2 Epidemiology 

Exhibit 9-1: 2010, Europe, Benign Prostatic Hyperplasia, Incidence, by Age 
Exhibit 9-2: Spain and Europe, Benign Prostatic Hyperplasia, Comparative Incidence and Prevalence 
Exhibit 9-3: Spain and Europe, Endometriosis, Comparative Prevalence 
Exhibit 9-4: Spain and Europe, Erectile Dysfunction, Comparative Incidence and Prevalence 
Exhibit 9-5: Spain and Europe, Infertility, Comparative Incidence and Prevalence 
Exhibit 9-6: Spain and Europe, Urinary Incontinence, Comparative Incidence and Prevalence 

10. RESPIRATORY DISORDERS

10.1 Acute Respiratory Distress Syndrome 
	10.1.1 Etiology 
	10.1.2 Epidemiology 
10.2 Apnea 
	10.2.1 Etiology 
	10.2.2 Epidemiology 
10.3 Asthma 
	10.3.1 Etiology 
	10.3.2 Epidemiology 
10.4 Cystic Fibrosis 
	10.4.1 Etiology 
	10.4.2 Epidemiology 
10.5 Emphysema 
	10.5.1 Etiology 
	10.5.2 Epidemiology 
10.6 Pneumothorax 
	10.6.1 Etiology 
	10.6.2 Epidemiology 
10.7 Respiratory Failure 
	10.7.1 Etiology 
	10.7.2 Epidemiology 
10.8 Restrictive Lung Disease 
	10.8.1 Etiology 
	10.8.2 Epidemiology 

Exhibit 10-1: Spain and Europe, Acute Respiratory Distress Syndrome, Comparative Incidence 
Exhibit 10-2: Spain and Europe, Apnea, Comparative Incidence and Prevalence 
Exhibit 10-3: Spain and Europe, Asthma, Comparative Incidence and Prevalence 
Exhibit 10-4: Spain and Europe, Cystic Fibrosis, Comparative Incidence and Prevalence 
Exhibit 10-5: Spain and Europe, Emphysema, Comparative Prevalence 
Exhibit 10-6: Spain and Europe, Pneumothorax, Comparative Incidence and Prevalence 
Exhibit 10-7: Spain and Europe, Respiratory Failure, Comparative Incidence and Prevalence 
Exhibit 10-8: Spain and Europe, Restrictive Lung Disease, Comparative Incidence and Prevalence 

11. WOUNDS

11.1 Diabetic Ulcers 
	11.1.1 Etiology 
	11.1.2 Epidemiology 
11.2 Pressure Ulcers 
	11.2.1 Etiology 
	11.2.2 Epidemiology 
11.3 Surgical Wounds 
	11.3.1 Etiology 
	11.3.2 Epidemiology 
11.4 Traumatic Wounds 
	11.4.1 Burns 
	11.4.2 Head Injuries, Lacerations, Contusions, and Abrasions 

Exhibit 11-1: Spain and Europe, Diabetic Ulcers, Comparative Incidence and Prevalence 
Exhibit 11-2: Spain and Europe, Pressure Ulcers, Comparative Incidence and Prevalence 
Exhibit 11-3: Spain and Europe, Surgical Wounds, Comparative Incidence 
Exhibit 11-4: Classification of Burns, by Mechanism of Injury 
Exhibit 11-5: Spain and Europe, Burns and Acute Traumatic Injury, Comparative Incidence 

12. SELECTED CONDITIONS CAUSED BY INFECTIOUS ORGANISMS

12.1 Chronic Bronchitis 
	12.1.1 Etiology 
	12.1.2 Epidemiology 
12.2 Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome 
	12.2.1 Etiology 
	12.2.2 Epidemiology 
12.3 Pneumonia 
	12.3.1 Etiology 
	12.3.2 Epidemiology 
12.4 Transmissible Spongiform Encephalopathies 
	12.4.1 Etiology 
	12.4.2 Epidemiology 
12.5 Tuberculosis 
	12.5.1 Etiology 
	12.5.2 Epidemiology 

Exhibit 12-1: Spain and Europe, Chronic Bronchitis, Comparative Prevalence 
Exhibit 12-2: Acquired Immune Deficiency Syndrome, Indicator Diseases 
Exhibit 12-3: Spain and Europe, Human Immunodeficiency Virus, Comparative Incidence and Prevalence 
Exhibit 12-4: Spain and Europe, Acquired Immune Deficiency Syndrome, Comparative Incidence and Prevalence 
Exhibit 12-5: Spain and Europe, Pneumonia, Comparative Incidence 
Exhibit 12-6: Spain and Europe, Transmissible Spongiform Encephalopathies, Comparative Incidence 
Exhibit 12-7: Spain and Europe, Tuberculosis, Comparative Incidence and Prevalence 



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