U.S. MARKETS FOR NEUROSURGICAL AND NEUROINTERVENTIONAL SURGICAL PRODUCTS

274 Pages | 83 Exhibits | 2011 Analysis | Forecasts Through 2015

OVERVIEW:
Medical conditions affecting the brain and associated branches of the central nervous system (CNS) afflict millions of people in the United States (U.S.) each year and are associated with high mortality rates and billions of dollars of direct and indirect medical costs. This new report from Medtech Insight provides an analyses of products, current and forecast markets, and suppliers of neurosurgical and neurointerventional devices in the U.S. Covered product markets in this report include cerebral embolectomy/thrombectomy systems, cerebrospinal fluid management systems, cranial closure and dura mater repair systems, embolization devices, external beam radiation therapy systems, image-guided navigation systems, neuroendoscopes, stenting systems, and surgical instruments and clipping systems. These devices are used for the prevention and treatment of various diseases and disorders including Alzheimer's disease, aneurysms, arteriovenous malformations, brain/CNS tumors, epilepsy, head trauma, hydrocephalus, Parkinson's disease, and stroke.

The increasing prevalence of neurologic diseases and disorders in the U.S. is just one of the factors that will drive growth of the U.S. market for neurosurgical and neurointerventional surgical devices during the forecast period covered by this report. This market, which was valued at approximately $1,261.3 million in 2010, is projected to increase in value at a compound annual rate of 7.8% over the forecast period, reaching an estimated $1,837.0 million in the year 2015.

TABLE OF CONTENTS:
EXECUTIVE SUMMARY

i. The Nervous System 
ii. Neurosurgical Products 
iii. Neurointerventional Products 
iv. Image-Guided Navigation Systems and External Beam Radiation Therapy Systems for Neurosurgery 
v. Combined Market Forecast 

Exhibit ES-1: 2010, Estimated Incidence and Prevalence of Selected Neurologic Diseases/Disorders 
Exhibit ES-2: Neurosurgical Products, Market Forecast, 2010-2015 
Exhibit ES-3: Neurointerventional Devices, Market Forecast, 2010-2015 
Exhibit ES-4: Image-Guided Navigation and External Beam Radiation Therapy Systems, Combined Market Forecast, 2010-2015 
Exhibit ES-5: Neurosurgical and Neurointerventional Surgical Products, Combined Market Forecast, 2010-2015 

1. CLINICAL OVERVIEW OF THE NERVOUS SYSTEM

1.1 The Brain and Cerebrovascular System 
	1.1.1 The Peripheral Nervous System 
1.2 Selected Neurologic Diseases/Disorders 
	1.2.1 Alzheimer's Disease 
		1.2.1.1 Etiology 
		1.2.1.2 Epidemiology
		1.2.1.3 Treatment Options 
			1.2.1.3.1 Device-Based Therapy 
			1.2.1.3.2 Drug Therapy 
			1.2.1.3.3 Surgery 
			1.2.1.3.4 Prevention 
	1.2.2 Cerebrovascular Disorders 
		1.2.2.1 Arteriovenous Malformation 
			1.2.2.1.1 Etiology 
			1.2.2.1.2 Epidemiology 
			1.2.2.1.3 Treatment Options 
			1.2.2.1.4 Device-Based Therapy 
			1.2.2.1.5 Drug Therapy 
			1.2.2.1.6 Surgery 
			1.2.2.1.7 Radiation Therapy 
		1.2.2.2 Cerebral Aneurysm 
			1.2.2.2.1 Etiology 
			1.2.2.2.2 Epidemiology 
			1.2.2.2.3 Treatment Options 
			1.2.2.2.4 Device-Based Therapy 
			1.2.2.2.5 Drug Therapy 
			1.2.2.2.6 Surgery 
			1.2.2.2.7 Other Modalities 
		1.2.2.3 Stroke 
			1.2.2.3.1 Etiology 
			1.2.2.3.2 Epidemiology 
			1.2.2.3.3 Treatment Options 
			1.2.2.3.4 Device-Based Therapy 
				1.2.2.3.4.1 Ischemic Stroke 
				1.2.2.3.4.2 Subarachnoid Hemorrhage 
			1.2.2.3.5 Drug Therapy 
			1.2.2.3.6 Prevention 
	1.2.3 Head Trauma 
		1.2.3.1 Etiology 
		1.2.3.2 Epidemiology 
		1.2.3.3 Treatment Options 
			1.2.3.3.1 Device-Based Therapy 
			1.2.3.3.2 Drug Therapy 
			1.2.3.3.3 Surgery 
			1.2.3.3.4 Other Modalities 
	1.2.4 Hydrocephalus and Increased Intracranial Pressure 
		1.2.4.1 Etiology 
		1.2.4.2 Epidemiology 
		1.2.4.3 Treatment Options 
			1.2.4.3.1 Device-Based Therapy 
			1.2.4.3.2 Drug Therapy 
			1.2.4.3.3 Surgery 
			1.2.4.3.4 Other Modalities 
	1.2.5 Parkinson's Disease 
		1.2.5.1 Etiology 
		1.2.5.2 Epidemiology 
		1.2.5.3 Treatment Options 
			1.2.5.3.1 Device-Based Therapy 
			1.2.5.3.2 Drug Therapy 
			1.2.5.3.3 Surgery 
			1.2.5.3.4 Other Modalities 
			1.2.5.3.5 Prevention 
	1.2.6 Tumors of the Brain and Central Nervous System 
		1.2.6.1 Etiology 
		1.2.6.2 Epidemiology 
		1.2.6.3 Treatment Options 
			1.2.6.3.1 Device-Based Therapy 
			1.2.6.3.2 Drug Therapy 
			1.2.6.3.3 Surgery 
			1.2.6.3.4 Other Modalities 

Exhibit 1-1: Anatomy of the Brain 
Exhibit 1-2: Alzheimer's Disease, Facts and Figures
Exhibit 1-3: Arteriovenous Malformation, Facts and Figures 
Exhibit 1-4: Cerebral Aneurysm, Facts and Figures 
Exhibit 1-5: Stroke, Facts and Figures 
Exhibit 1-6: Hemorrhagic Stroke, Facts and Figures 
Exhibit 1-7: Ischemic Stroke, Facts and Figures 
Exhibit 1-8: Head Trauma and Brain Injury, Facts and Figures 
Exhibit 1-9: Hydrocephalus, Facts and Figures 
Exhibit 1-10: 2009, Parkinson's Disease, Facts and Figures 
Exhibit 1-11: Brain/Central Nervous System Tumors, Facts and Figures 

2. NEUROSURGICAL PRODUCTS MARKET

2.1 Products/Technologies 
	2.1.1 Surgical Instruments 
		2.1.1.1 Handheld Instruments 
			2.1.1.1.1 Products/Technologies 
			2.1.1.1.2 Market Forecast 
			2.1.1.1.3 Competitive Analysis 
		2.1.1.2 Powered Instruments and Accessories 
			2.1.1.2.1 Products/Technologies 
			2.1.1.2.2 Market Forecast 
			2.1.1.2.3 Competitive Analysis 
		2.1.1.3 Electrosurgical Systems 
			2.1.1.3.1 Products/Technologies 
			2.1.1.3.2 Market Forecast 
			2.1.1.3.3 Competitive Analysis 
		2.1.1.4 Ultrasonic Aspiration Systems 
			2.1.1.4.1 Products/Technologies 
			2.1.1.4.2 Market Forecast 
			2.1.1.4.3 Competitive Analysis 
	2.1.2 Surgical Clipping Systems for Cerebral Aneurysms and Arteriovenous Malformations 
		2.1.2.1 Products/Technologies 
		2.1.2.2 Market Forecast 
		2.1.2.3 Competitive Analysis 
	2.1.3 Cerebrospinal Fluid Management Systems 
		2.1.3.1 Products/Technologies 
			2.1.3.1.1 Implantable Cerebrospinal Fluid Shunts 
			2.1.3.1.2 External Cerebrospinal Fluid Drainage Systems 
		2.1.3.2 Market Forecast 
		2.1.3.3 Competitive Analysis 
	2.1.4 Cranial Closure and Dura Mater Repair Systems 
		2.1.4.1 Cranial Fixation and Other Skull Closure Devices 
		2.1.4.2 Bone Cement and Bone Substitute Materials 
		2.1.4.3 Dura Mater Substitutes/Repair Systems 
		2.1.4.4 Market Forecast 
		2.1.4.5 Competitive Analysis 
2.2 Neurosurgical Products, Combined Procedure Volumes Forecast 
2.3 Neurosurgical Products, Combined Market Forecast 

Exhibit 2-1: Indications for Handheld Neurosurgical Instruments 
Exhibit 2-2: Craniotomy Tray, Representative Instruments 
Exhibit 2-3: 2011, Selected Handheld Neurosurgical Instruments 
Exhibit 2-4: Handheld Neurosurgical Instruments, Market Forecast, 2010-2015 
Exhibit 2-5: 2010, Handheld Neurosurgical Instruments Market, Share by Supplier 
Exhibit 2-6: Selected Powered Neurosurgical Instruments 
Exhibit 2-7: 2011, Selected Powered Neurosurgical Instruments 
Exhibit 2-8: Powered Neurosurgical Instruments, Market Forecast, 2010-2015 
Exhibit 2-9: 2010, Powered Neurosurgical Instruments Market, Share by Supplier 
Exhibit 2-10: 2011, Selected Electrosurgical Products 
Exhibit 2-11: Electrosurgical Products for Neurosurgical Applications, Market Forecast, 2010-2015 
Exhibit 2-12: 2010, Electrosurgical Products Market, Share by Supplier 
Exhibit 2-13: 2011, Selected Ultrasonic Aspiration Products 
Exhibit 2-14: Ultrasonic Aspiration Products for Neurosurgical Applications, Market Forecast, 2010-2015 
Exhibit 2-15: 2010, Ultrasonic Aspiration Products Market, Share by Supplier 
Exhibit 2-16: 2011, Selected Cerebral Aneurysm and Arteriovenous Malformation Clipping Systems 
Exhibit 2-17: Cerebral Aneurysm and Arteriovenous MalformationClipping Systems, Market Forecast, 2010-2015 
Exhibit 2-18: 2010, Cerebral Aneurysm and Arteriovenous Malformation Clipping Systems Market, Share by Supplier 
Exhibit 2-19: Hydrocephalus Valve Implants, Typical Pressure/ Flow Relationships 
Exhibit 2-20: 2011, Selected Cerebrospinal Fluid Management Products 
Exhibit 2-21: Cerebrospinal Fluid Management Products, Market Forecast, 2010-2015 
Exhibit 2-22: 2010, Cerebrospinal Fluid Management Products Market, Share by Supplier 
Exhibit 2-23: 2011, Selected Cranial Fixation/Closure Devices and Bone Replacements 
Exhibit 2-24: 2011, Selected Dural Substitutes/Repair Systems 
Exhibit 2-25: Cranial Fixation/Closure Devices and Dural Substitutes/Repair Systems, Market Forecast, 2010-2015 
Exhibit 2-26: 2010, Cranial Fixation/Closure Devices Market, Share by Supplier 
Exhibit 2-27: 2010, Dural Substitutes/Repair Systems Market, Share by Supplier 
Exhibit 2-28: Neurosurgery, Procedure Volumes Forecast, 2010-2015 
Exhibit 2-29: Neurosurgical Products, Combined Market Forecast, 2010-2015 
Exhibit 2-30: 2010, Neurosurgical Products Market, Share by Segment 

3. NEUROINTERVENTIONAL DEVICES MARKET

3.1 Cerebral Aneurysm and Arteriovenous Malformation Embolization Systems 
	3.1.1 Products/Technologies 
	3.1.2 Market Forecast 
	3.1.3 Competitive Analysis 
3.2 Embolic Coil-Containment Stenting Systems 
	3.2.1 Products/Technologies 
	3.2.2 Market Forecast 
	3.2.3 Competitive Analysis 
3.3 Carotid Artery Stenting Systems 
	3.3.1 Products/Technologies 
	3.3.2 Market Forecast 
	3.3.3 Competitive Analysis 
3.4 Intracranial Stenting Systems for Ischemic Stroke Indications 
	3.4.1 Products/Technologies 
	3.4.2 Market Forecast 
3.5 Neuroendoscopes 
	3.5.1 Products/Technologies 
	3.5.2 Market Forecast 
	3.5.3 Competitive Analysis 
3.6 Cerebral Embolectomy/Thrombectomy Systems 
	3.6.1 Products/Technologies 
	3.6.2 Market Forecast 
	3.6.3 Competitive Analysis 
3.7 Neurointerventional Devices, Combined Procedure Volumes Forecast 
3.8 Neurointerventional Devices, Combined Market Forecast 

Exhibit 3-1: 2011, Selected Embolic Agents and  Transcatheter Delivery Devices 
Exhibit 3-2: Cerebral Aneurysm and Arteriovenous Malformation Endovascular Embolization Systems,  Market Forecast, 2010-2015 
Exhibit 3-3: 2010, Cerebral Aneurysm and Arteriovenous Malformation Endovascular Embolization Systems, Share by Supplier 
Exhibit 3-4: 2011, Selected Neurointerventional Stenting Systems for Use with Embolic Coils 
Exhibit 3-5: Neurointerventional Embolic Coil-Containment Stenting Systems, Market Forecast, 2010-2015 
Exhibit 3-6: 2010, Neurointerventional Embolic Coil-Containment Stenting Systems, Share by Supplier 
Exhibit 3-7: 2011, Selected Carotid Artery Stenting and Embolic Protection Systems 
Exhibit 3-8: Distally Protected Carotid Artery Stenting Systems, Market Forecast, 2010-2015 
Exhibit 3-9: 2010, Distally Protected Carotid Artery Stenting Systems, Share by Supplier 
Exhibit 3-10: 2011, Selected Intracranial Stenting Systems 
Exhibit 3-11: Intracranial Stenting Systems, Market Forecast, 2010-2015 
Exhibit 3-12: Selected Neuroendoscopic Techniques 
Exhibit 3-13: 2011, Selected Neuroendoscopes 
Exhibit 3-14: Neuroendoscopes, U.S. Market Forecast, 2010-2015 
Exhibit 3-15: 2010, Neuroendoscopes, Share by Supplier 
Exhibit 3-16: 2011, Selected Cerebral Embolectomy/Thrombectomy Systems 
Exhibit 3-17: 2011, Selected Cerebral Embolectomy/Thrombectomy Systems Under Development 
Exhibit 3-18: Cerebral Embolectomy/Thrombectomy Systems, Market Forecast, 2010-2015 
Exhibit 3-19: 2010, Cerebral Embolectomy/Thrombectomy Systems, Share by Supplier 
Exhibit 3-20: Neurointerventional Procedures, Combined Procedure Volumes Forecast, 2010-2015 
Exhibit 3-21: Neurointerventional Devices, Combined Market Forecast, 2010-2015 

4. IMAGE-GUIDED NAVIGATION AND EXTERNAL BEAM RADIATION THERAPY SYSTEMS FOR NEUROSURGERY

4.1 Image-Guided Surgery 
	4.1.1 Imaging Sources/Techniques 
		4.1.1.1 Preoperative Images 
		4.1.1.2 Direct Real-Time Intraoperative Imaging 
		4.1.1.3 Intermittent Intraoperative Imaging Combined with Computerized Tracking and Navigation Tools 
		4.1.1.4 Computer-Generated Three-Dimensional Images 
4.2 Common Neurosurgical Applications for Image-Guided Surgery 
	4.2.1 Central Nervous System Tumor Resection 
	4.2.2 Epilepsy Surgery 
	4.2.3 Deep Brain Stimulation for Parkinson's Disease 
4.3 Stereotactic Surgical Navigation Systems 
	4.3.1 Frame-Based Stereotactic Systems 
	4.3.2 Frameless Stereotactic Systems 
4.4 Intraoperative Navigation 
	4.4.1 Registration Methods and Techniques 
	4.4.2 Intraoperative Tracking Devices 
	4.4.3 Computer Interfaces 
	4.4.4 Image-Guided Surgical Instruments 
	4.4.5 Supporting Data Management Infrastructure 
4.5 Image-Guided Surgical Navigation Systems Market 
	4.5.1 Products 
	4.5.2 Market Analysis 
	4.5.3 Competitive Analysis 
4.6 Image-Guided External Beam Radiation Therapy Systems Market 
	4.6.1 Products/Technologies 
		4.6.1.1 The Gamma Knife 
		4.6.1.2 Linear Accelerator-Based Systems 
	4.6.2 Market Analysis 
	4.6.3 Competitive Analysis 

Exhibit 4-1: Image-Guided Navigation and External Beam Radiation Therapy Systems, Combined Market Forecast, 2010-2015 
Exhibit 4-2: Benefits and Drawbacks of Image-Guided/Computer-Assisted Surgery Techniques 
Exhibit 4-3: Typical Clinical Applications of Image-Guided/Computer-Assisted Surgery Techniques 
Exhibit 4-4: Characteristics of Commonly Performed Image-Guided Neurosurgical Procedures 
Exhibit 4-5: Image-Guided/Computer-Assisted Neurosurgery, Procedure Volumes Forecast, 2010-2015 
Exhibit 4-6: Comparison of Framed and Frameless Stereotactic Systems 
Exhibit 4-7: Comparative Advantages and Disadvantages of Extrinsic and Intrinsic Registration Systems 
Exhibit 4-8: Comparative Characteristics of Commonly Used Intraoperative Tracking Systems 
Exhibit 4-9: 2011, Selected Image-Guided/Computer-Assisted Surgical Navigation Systems 
Exhibit 4-10: Image-Guided/Computer-Assisted Surgical Navigation Systems, Market Forecast, 2010-2015 
Exhibit 4-11: 2010, Image-Guided/Computer-Assisted Surgical Navigation Systems Market, Share by Supplier 
Exhibit 4-12: The Gamma Knife Stereotactic Radiosurgery Device 
Exhibit 4-13: Selected Radiosurgery Treatment Systems 
Exhibit 4-14: 2011, Selected External Beam Radiation Therapy Systems 
Exhibit 4-15: External Beam Radiation Therapy Systems, Market Forecast, 2010-2015 
Exhibit 4-16: 2010, External Beam Radiation Therapy Systems Market, Share by Supplier 

5. COMPANY PROFILES

5.1 Abbott Laboratories 
5.2 Brainlab, Inc. 
5.3 B. Braun Melsungen AG 
5.4 Covidien PLC 
5.5 Elekta AB 
5.6 Integra LifeSciences Corporation 
5.7 Medtronic, Inc. 
5.8 Mizuho Ikakogyo Co. LTD 
5.9 Penumbra, Inc. 
5.10 Synthes, Inc. 
5.11 Varian Medical Systems, Inc. 

APPENDIX: COMPANY LISTING


COMPANIES COVERED:

  1. Abbott Laboratories
  2. Brainlab, Inc.
  3. B. Braun Melsungen AG
  4. Covidien PLC
  5. Elekta AB
  6. Integra LifeSciences Corporation
  7. Medtronic, Inc.
  8. Mizuho Ikakogyo Co. LTD
  9. Penumbra, Inc.
  10. Synthes, Inc.
  11. Varian Medical Systems, Inc.
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