This report provides a summary of the nearly $5 billion global spinal implants market, which (for the purposes of this report) includes the following selected product segments in the top 5 markets of the European Union (France, Germany, Italy, Spain, the U.K.), as well as Japan and the U.S.:
This dynamic, new report from Medtech Insight includes a profile of dozens of selected leading products; clinical study results; a comprehensive market analysis, including expected segment growth, drivers/limiters, and market forecasts (from 2015-2020); and competitive analysis, including estimated 2015 market share by supplier. Emerging technologies (cell-based therapies, tissue engineering products and biologics) are also profiled.
EXECUTIVE SUMMARY i. Global Spinal Implants Market ii. Methodology Exhibit ES-1: Global Spinal Implants Market, Combined Sales, 2015-2020 Exhibit ES-2: 2015, Global Spinal Implants Market, Share by Segment 1. CLINICAL OVERVIEW 1.1 Anatomy of the Human Spine 1.1.1 Curvature of the Spine 1.1.2 Vertebrae 1.1.3 Cervical Spine 1.1.4 Thoracic Spine 1.1.5 Lumbar Spine 1.1.6 Intervertebral Discs 1.1.7 Spinal Cord 1.1.8 Bone Physiology and Remodeling 1.2 Spinal Disorders 1.2.1 Degenerative Disc Disease 1.2.2 Herniated Disc 1.2.3 Spinal Stenosis 1.2.4 Spondylosis 1.2.5 Spondylolisthesis 1.2.6 Rheumatoid Arthritis 1.2.7 Paget's Disease 1.2.8 Osteoporosis 1.2.9 Spinal Fractures 1.3 Spinal Treatment Options 1.3.1 Spinal Decompression Technologies 184.108.40.206 Corpectomy 220.127.116.11 Disectomy 18.104.22.168 Foraminotomy/Foraminectomy 22.214.171.124 Laminotomy/Laminectomy 126.96.36.199 Facetectomy Exhibit 1-1: Prevalence of Lower Back Pain, Selected Countries Exhibit 1-2: The Human Spine Exhibit 1-3: Vertebra Exhibit 1-4: Intevertebral Disc Exhibit 1-5: The Spinal Cord Exhibit 1-6: Illustrations of Disc Damage and Stenosis Exhibit 1-7: Example of Spine Nerve Compression Exhibit 1-8: Stages of Spondylolisthesis Exhibit 1-9: Osteoporosis Exhibit 1-10: Vertebral Compression Fracture Exhibit 1-11: Discectomy and Laminectomy Procedure Volumes Forecast, Top 5 EU, U.S., and Japan, 2015-2020 2. ARTIFICIAL CERVICAL AND LUMBAR DISCS 2.1 Fusion vs. Non-Fusion 2.2 Total Disc Replacement 2.3 Artificial Cervical Discs 2.3.1 Selected Clinical Evidence Regarding Artificial Cervical Discs 2.3.2 Selected Artificial Cervical Discs 188.8.131.52 Bryan Cervical Artificial Disc 184.108.40.206 Prestige ST Cervical Artificial Disc 220.127.116.11 ProDisc-C Disc 18.104.22.168 NuVasive PCM Cervical Disc 22.214.171.124 Mobi-C Artificial Cervical Disc 126.96.36.199 SECURE-C Artificial Cervical Disc 2.4 Artificial Lumbar Discs 2.4.1 Selected Clinical Evidence Regarding Artificial Lumbar Discs 2.4.2 Selected Artificial Lumbar Discs 188.8.131.52 Charite 184.108.40.206 ProDisc-L 220.127.116.11 MobiDisc 18.104.22.168 M6 22.214.171.124 ActivL 2.5 Market Analysis 2.6 Competitive Analysis 2.6.1 Artificial Cervical Discs 2.6.2 Artificial Lumbar Discs Exhibit 2-1: Artificial Lumbar Disc Replacement Exhibit 2-2: Selected FDA-Approved Cervical Total Disc Replacement Devices Exhibit 2-3: Selected FDA-Approved Lumbar Total Disc Replacement Devices Exhibit 2-4: Artificial Cervical Discs Market, Selected Countries, 2015-2020 Exhibit 2-5: Artificial Lumbar Discs Market, Selected Countries, 2015-2020 Exhibit 2-6: 2015, Artificial Cervical Discs Market, Share by Supplier Exhibit 2-7: 2015, Artificial Lumbar Discs Market, Share by Supplier 3. DYNAMIC STABILIZATION DEVICES 3.1 Types of Devices 3.2 Interspinous Process Decompression Devices 3.2.1 DIAM 3.2.2 X-Stop 3.2.3 Coflex 3.2.4 InSpace 3.2.5 UniWallis 3.3 Pedicle Screw-Based Posterior Dynamic Stablization Devices 3.3.1 Dynesys 3.3.2 Dynamic Stabilization System 3.3.3 Transition 3.3.4 Isobar 3.4 Market Forecast 3.5 Competitive Analysis Exhibit 3-1: Selected Interspinous Process Spacers Exhibit 3-2: Selected Pedicle Screw-Based Dynamic Stabilization Systems Exhibit 3-3: Dynamic Stabilization Devices Market, Selected Countries, 2015-2020 Exhibit 3-4: 2015, Dynamic Stabilization Devices Market, Share by Supplier 4. OTHER MOTION PRESERVATION DEVICES 4.1 Facet Replacement Products 4.1.1 Market Analysis 4.2 Annulus Repair 4.2.1 Market Analysis 4.3 Disc Nucleus Replacement Technologies Exhibit 4-1: Annulus Repair Procedure Volumes Forecast, Selected Countries, 2015-2020 Exhibit 4-2: Annulus Repair Market Forecast, Selected Countries, 2015-2020 5. SPINAL FUSION INSTRUMENTATION 5.1 Cervical Fusion 5.1.1 Anterior Cervical Fusion 126.96.36.199 Anterior Cervical Plates 188.8.131.52 Anterior Cervical Plates Products 184.108.40.206.1 Aesculap/B. Braun Melsungen 220.127.116.11.2 Alphatec Spine 18.104.22.168.3 DePuy Synthes 22.214.171.124.4 Medtronic 126.96.36.199.5 Stryker 188.8.131.52.6 Zimmer Biomet 5.1.2 Posterior Cervical Fusion 5.1.3 Cervical Pedicle Screw Systems 5.1.4 Interbody Cervical Fusion 184.108.40.206 Device Design and Materials 220.127.116.11 Selected Clinical Evidence Regarding Cervical Cages 18.104.22.168 Selected Cervical Cage Products 5.2 Thoracic and Lumbar Fusion 5.2.1 Thoracic and Lumbar Fusion, by Approach 5.2.2 Selected Anterior Lumbar Plating Systems 5.2.3 Selected Clinical Evidence Regarding Interbody Fusion (IBF) Cages 5.2.4 Selected Lumbar Interbody Fusion Cages 5.3 Posterior Spinal Fixation Devices 5.3.1 Pedicle Screw Systems 5.3.2 Selected Clinical Evidence Regarding Pedicle Screw Systems 5.3.3 Selected Pedicle Screw Fixation Systems 5.4 Market Analysis 5.4.1 Interbody Fusion Devices-Procedures Volumes Forecast and Market Forecast 5.4.2 Pedicle Screw Market Forecast 5.4.3 Anterior Cervical Plates Market Forecast 5.4.4 Spinal Fusion Instrumentation Combined Market Forecast 5.5 Competitive Analysis 5.5.1 Pedicle Screws 5.5.2 Interbody Fusion Devices 5.5.3 Anterior Column Plating Exhibit 5-1: Classification of Anterior Cervical Plates Exhibit 5-2: Selected Anterior Cervical Plate Systems Exhibit 5-3: Selected Cervical Cage Systems Exhibit 5-4: Selected Anterior Lumbar Plating Systems Exhibit 5-5: Selected Interbody Fusion Devices Exhibit 5-6: Selected Pedicle Screw Fixation Systems Exhibit 5-7: Interbody Fusion Procedure Volumes Forecast, by Country, 2015-2020 ('000s) Exhibit 5-8: Interbody Fusion Devices Market Forecast, by Country, 2015-2020 ($M) Exhibit 5-9: Pedicle Screw Market Forecast, by Country 2015-20 ($M) Exhibit 5-10: Anterior Column Plating Market Forecast, by Country 2015-20 ($M) Exhibit 5-11: Combined Market Forecast, Spinal Instrumentation, by Country 2015-20 ($M) Exhibit 5-12: 2015, Pedicle Screw Market, Share by Supplier Exhibit 5-13: 2015, Interbody Fusion Devices Market, Share by Supplier Exhibit 5-14: 2015, Anterior Column Plating Systems Market, Share by Supplier 6. VERTEBRAL COMPRESSION FRACTURE TREATMENT 6.1 Vertebroplasty 6.1.1 Clinical Evidence Regarding Vertebroplasty 6.1.2 Polymethylmethacrylate Alternatives 6.1.3 Selected Vertebroplasty Products 6.2 Kyphoplasty 6.3 Percutaneous Vertebral Augmentation Systems 6.3.1 New or Emerging Percutaneous Vertebral Augmentation Systems 6.3.2 Selected Percutaneous Vertebral Augmentation Systems 6.4 Procedure Volumes Forecast-Kyphoplasty and Vertebroplasty 6.5 Market Forecast 6.6 Competitive Analysis-Vertebroplasty 6.7 Competitive Analysis-Balloon Kyphoplasty and Percutaneous Vertebral Augmentation Systems Exhibit 6-1: Vertebroplasty Indications and Contraindications Exhibit 6-2: Selected Vertebroplasty Products Exhibit 6-3: Selected Percutaneous Vertebral Augmentation Products Exhibit 6-4: Balloon Kyphoplasty and Vertebroplasty Procedure Volumes Forecast, Top 5 EU, U.S. and Japan, 2015-2020 Exhibit 6-5: Balloon Kyphoplasty/Percutaneous Vertebral Augmentation Systems and Vertebroplasty Market Forecast, Top 5 EU, U.S. and Japan, 2015-2020 Exhibit 6-6: 2015, Vertebroplasty Products Market, Share by Supplier Exhibit 6-7: 2015, Balloon Kyphoplasty and Percutaneous Vertebral Augmentation Systems Market, Share by Supplier 7. EMERGING TECHNOLOGIES 7.1 Stem Cell Therapy 7.1.1 Selected Products Under Development 22.214.171.124 Mesoblast 126.96.36.199 NuVasive 188.8.131.52 ISTO Technologies 184.108.40.206 Orthofix 7.2 Biologics 7.2.1 Selected Products Under Development 220.127.116.11 Alphatec Spine 18.104.22.168 Stryker 22.214.171.124 Zimmer Biomet 7.3 Tissue Engineering 7.3.1 Selected Products Under Development 126.96.36.199 DiscGenics 7.4 Market Analysis for Emerging Technologies Exhibit 7-1: Selected Limitations of Alternative Biological Therapies for Spinal Disc Repair 8. GLOBAL SPINAL IMPLANTS MARKET i. Artificial Cervical and Lumbar Discs ii. Dynamic Stabilization Devices iii. Annulus Repair Products iv. Spinal Fusion Instrumentation v. Vertebral Compression Fracture Treatment Products vi. Global Spinal Implants Market Exhibit 8-1: Global Spinal Implants Market, 2015-2020 Exhibit 8-2: 2015, Global Spinal Implants Market, Share by Segment Exhibit 8-3: 2020, Global Spinal Implants Market, Share by Segment APPENDIX A: COMPANY LISTING APPENDIX B: BIBLIOGRAPHY