EUROPEAN MARKETS FOR BONE GRAFT SUBSTITUTE PRODUCTS FOR SPINAL FUSION

112 Pages | 51 Exhibits | 2011 Analysis | Forecasts Through 2016

OVERVIEW:
The European market for bone graft substitute products for spinal fusion is projected to experience significant growth over the next half-decade due to a number of factors, particularly an increased prevalence of degenerative disc disease. This new report from Medtech Insight/Elsevier Business Intelligence provides market forecasts and analysis of the European market for bone graft substitute products including bone morphogenetic proteins, demineralized bone matrix, and synthetic bone graft substitutes.

In 2010, the value of the European market for bone graft substitute products for spinal fusion totaled approximately $177.1 million; during the forecast period covered by this report, this market is projected to grow at a compound annual rate of 17.3%, reaching an estimated $461.7 million in the year 2016.

This newly published report from Medtech Insight includes a clinical overview of the various bone graft substitutes in use in Europe, a review of the leading drivers and limiters of the European bone graft substitutes products market, and an analysis of the leading competitors and their individual market shares. This is the second in a two-part series of reports on the European market for spinal fusion products.

TABLE OF CONTENTS:
EXECUTIVE SUMMARY

i. Clinical Overview 
ii. Demineralized Bone Matrix 
	a. Market Forecast 
iii. Synthetic Bone Graft Substitutes 
	a. Market Forecast 
iv. Bone Morphogenetic Proteins 
	a. Market Forecast 
v. Combined Market Analysis 
vi. Methodology 

Exhibit ES-1: Europe, Bone Graft Substitute Products for Spinal Fusion, Combined Market Forecast, 2010-2016 

1. ANATOMY AND PHYSIOLOGY OF THE SPINE

1.1 Spinal Anatomy 
	1.1.1 Vertebrae 
	1.1.2 Spinal Canal 
1.2 Selected Spinal Disorders 
	1.2.1 Disc Herniation 
	1.2.2 Degenerative Disc Disease 
		1.2.2.1 Arthritis 
			1.2.2.1.1 Osteoarthritis 
			1.2.2.1.2 Rheumatoid Arthritis 
			1.2.2.1.3 Ankylosing Spondylitis 
		1.2.2.2 Osteoporosis 
		1.2.2.3 Spondylosis 
	1.2.3 Abnormal Curvature of the Spine 
		1.2.3.1 Scoliosis 
		1.2.3.2 Kyphosis and Lordosis 
	1.2.4 Spondylolisthesis 
	1.2.5 Stenosis 
	1.2.6 Spinal Tumors 
	1.2.7 Traumatic Spinal Injuries 
	1.2.8 Vertebral Fractures 

Exhibit 1-1: Lateral View of the Spinal Column 
Exhibit 1-2: Axial and Lateral Views of the Thoracic Vertebrae 
Exhibit 1-3: Axial and Lateral Views of the Lumbar Vertebrae 
Exhibit 1-4: Stages of Disc Herniation 
Exhibit 1-5: Common Degenerative Spinal Disorders 
Exhibit 1-6: Lumbar and Thoracic Scoliosis 
Exhibit 1-7: A Kyphotic versus a Normal Spine 
Exhibit 1-8: A Lordotic versus a Normal Spine 
Exhibit 1-9: A Healthy Cervical Spine Compared with Spinal Stenosis and Disc Herniation 

2. THE EUROPEAN MARKET FOR DEMINERALIZED BONE MATRIX  AND SYNTHETIC BONE GRAFT SUBSTITUTES

2.1 Bone Graft Characteristics 
2.2 Demineralized Bone Matrix 
	2.2.1 Selected Demineralized Bone Matrix Products 
		2.2.1.1 DePuy/Johnson & Johnson 
		2.2.1.2 Integra LifeSciences 
		2.2.1.3 Medtronic 
		2.2.1.4 Scient'x/Alphatec Spine 
		2.2.1.5 Smith & Nephew 
		2.2.1.6 Wright Medical Technology/Wright Medical Group 
		2.2.1.7 Zimmer 
2.3 Synthetic Bone Graft Substitutes 
	2.3.1 Selected Synthetic Bone Graft Substitute Products 
		2.3.1.1 Biomet 
		2.3.1.2 DePuy/Johnson & Johnson 
		2.3.1.3 Graftys 
		2.3.1.4 Integra LifeSciences 
		2.3.1.5 LDR Medical/LDR Holding 
		2.3.1.6 Medtronic 
		2.3.1.7 Smith & Nephew 
		2.3.1.8 Synthes 
		2.3.1.9 Wright Medical Technology/Wright Medical Group 
		2.3.1.10 Zimmer 
2.4 Market Analysis 
2.5 Competitive Analysis 

Exhibit 2-1: 2011, Selected Demineralized Bone Matrix Products 
Exhibit 2-2: 2011, Selected Synthetic Bone Graft Substitute Products 
Exhibit 2-3: Europe, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-4: France, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-5: Germany, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-6: Italy, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-7: Spain, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-8: United Kingdom, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-9: Benelux, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-10: Nordic Countries, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-11: Rest of Europe, Bone Graft Substitutes, Market Forecast, 2010-2016 
Exhibit 2-12: 2010, Europe, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-13: 2010, France, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-14: 2010, Germany, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-15: 2010, Italy, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-16: 2010, Spain, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-17: 2010, United Kingdom, Demineralized Bone Matrix Products Market, Share by Supplier
Exhibit 2-18: 2010, Benelux, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-19: 2010, Nordic Countries, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-20: 2010, Rest of Europe, Demineralized Bone Matrix Products Market, Share by Supplier 
Exhibit 2-21: 2010, Europe, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-22: 2010, France, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-23: 2010, Germany, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-24: 2010, Italy, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-25: 2010, Spain, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-26: 2010, United Kingdom, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-27: 2010, Benelux, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-28: 2010, Nordic Countries, Synthetic Bone Graft Substitutes Market, Share by Supplier 
Exhibit 2-29: 2010, Rest of Europe, Synthetic Bone Graft Substitutes Market, Share by Supplier 

3. THE EUROPEAN MARKET FOR RECOMBINANT BONE  MORPHOGENETIC PROTEIN PRODUCTS FOR SPINAL FUSION

3.1 Clinical Overview 
3.2 Products 
	3.2.1 InductOs 
	3.2.2 Opgenra 
3.3 Market Analysis 
3.4 Competitive Analysis 

Exhibit 3-1: Selected Bone Morphogenetic Proteins 
Exhibit 3-2: 2011, Selected Recombinant Bone Morphogenetic Protein Products for Spinal Fusion 
Exhibit 3-3: Europe, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-4: France, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-5: Germany, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-6: Italy, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-7: Spain, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-8: United Kingdom, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-9: Benelux, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-10: Nordic Countries, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-11: Rest of Europe, Bone Morphogenetic Protein Products, Market Forecast, 2010-2016 
Exhibit 3-12: 2010, Europe, Bone Morphogenetic Protein Products Market, By Country 

4. COMPANY PROFILES

4.1 DePuy Spine, Inc./Johnson & Johnson 
4.2 Graftys SA 
4.3 Integra LifeSciences Corporation 
4.4 LDR Medical/LDR Holding 
4.5 Medtronic, Inc. 
4.6 Scient'x SA/Alphatec Holdings, Inc. 
4.7 Smith & Nephew PLC 
4.8 Synthes, Inc. 
4.9 Wright Medical Technology, Inc./Wright Medical Group 
4.10 Zimmer Holdings, Inc. 

APPENDIX:  COMPANY LISTING


COMPANIES COVERED:

  1. Aap Implantate AG
  2. ApaTech/Baxter International
  3. Argomedical GmbH
  4. ARTOSS GmbH
  5. Astellas Pharma, Inc.
  6. Biocomposites Ltd.
  7. Biomatlante
  8. Biomet, Inc.
  9. BoneSupport AB
  10. Cerapedics, Inc.
  11. Curasan AG
  12. DePuy Spine, Inc./ Johnson & Johnson
  13. DOT GmbH
  14. Etex Corporation
  15. Exactech Inc.
  16. Graftys SA
  17. Integra LifeSciences Corporation
  18. Kasios
  19. Kensey Nash Corporation
  20. LDR Holding Corporation
  21. Mathys Ltd Bettlach
  22. Medtronic, Inc.
  23. NuVasive, Inc.
  24. Olympus Biotech International/Olympus Corporation
  25. Orthofix Holdings, Inc.
  26. Orthovita, Inc.
  27. Scient'x Group SAS/Alphatec Spine, Inc./Alphatec Holding
  28. Smith & Nephew plc
  29. Stryker Corporation
  30. Synthes GmbH
  31. Teknimed SA
  32. Wright Medical Technology, Inc./ Wright Medical Group
  33. Wyeth Pharmaceuticals, Inc./ Pfizer, Inc.
  34. Zimmer Holdings Inc.
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