EUROPEAN MARKETS FOR CURRENT AND EMERGING BIOMATERIAL-BASED ARTHROSCOPY PRODUCTS

331 Pages | 93 Exhibits | 2006 Analysis | Forecasts Through 2010

OVERVIEW:
The European biomaterials-based arthroscopy products market, valued at approximately $550.3 million in 2005, offers considerable commercial potential. Due to the continuing growth and aging of the European population, there will be a steady demand for both new, emerging biomaterials-based arthroscopy products, as well as older, established products.

Viscosupplementation products represented the largest segment of the European biomaterials-based arthroscopy products market in 2005, capturing approximately $322.8 million or 58.7% of total sales; bioresorbable tissue fixation products represented the second-largest segment of the overall market in 2005, with approximately $102.9 million or 18.6% of total sales. By the year 2010, European biomaterials-based arthroscopic surgery products revenues are projected to reach approximately $945.1 million, with most of this activity attributable to sales of viscosupplementation products. Over the forecast period covered by this report, sales of viscosupplementation products are expected to increase at a brisk compound annual rate of 10.2%, reaching approximately $526.4 million in the year 2010.

This dynamic report from Medtech Insight includes analyses of products and technologies, current and forecast markets, competitors, and opportunities in European markets for biomaterial-based arthroscopic surgery products.

Covered topics in this report include arthroscopic suturing devices, autologous cultured chondrocytes, bioresorbable tissue fixation devices, and viscosupplementation products.

TABLE OF CONTENTS:

EXECUTIVE SUMMARY

i.   European Healthcare Markets

ii.   Musculoskeletal System Overview

iii.  Orthopedic Tissue Grafts, Placement Volumes and Products Markets

iv.  Bone Graft Substitutes, Placement Volumes and Products Markets

v.  Bone Growth Factors, Placement Volumes and Products Markets

vi.  Arthroscopic Devices, Placement Volumes and Products Markets

 

1. EUROPEAN HEALTHCARE MARKET OVERVIEW

1.1 The European Union

1.1.1 A Common Currency

1.1.2 Regulatory Policies

1.1.3 Reimbursement

1.1.4 Factors Affecting Healthcare Delivery

1.1.4.1 Aging Population

1.1.4.2 Cost Containment

1.1.4.3 Industry Consolidation

1.1.4.4 Managed Care

1.1.5 Healthcare Spending

1.2 Selected European National Healthcare Profiles

1.2.1 France

1.2.1.1 Healthcare Organization and Reform

1.2.1.2 Hospital Services

1.2.1.3 Medical Device Reimbursement

1.2.2 Germany

1.2.2.1 Healthcare Organization and Reform

1.2.2.2 Hospital Services

1.2.2.3 Medical Device Reimbursement

1.2.3 Italy

1.2.3.1 Healthcare Organization and Reform

1.2.3.2 Hospital Services

1.2.3.3 Medical Device Reimbursement

1.2.4 Spain

1.2.4.1 Healthcare Organization and Reform

1.2.4.2 Hospital Services

1.2.4.3 Medical Device Reimbursement

1.2.5 United Kingdom

1.2.5.1 Healthcare Organization and Reform

1.2.5.2 Hospital Services

1.2.5.3 Medical Device Reimbursement

1.2.6 Rest of Europe

1.2.6.1 Healthcare Organization and Reform

1.2.6.2 Hospital Services

1.2.6.3 Medical Device Reimbursement

 

Exhibit 1-1: European Union, Medical Devices Risk Classification System

Exhibit 1-2: European Union, Population Statistics Comparison, 1994 and 2004

Exhibit 1-3: France, Selected National Healthcare Statistics

Exhibit 1-4: Germany, Selected National Healthcare Statistics

Exhibit 1-5: Italy, Selected National Healthcare Statistics

Exhibit 1-6: Spain, Selected National Healthcare Statistics

Exhibit 1-7: United Kingdom, Selected National Healthcare Statistics

 

2. MUSCULOSKELETAL SYSTEM OVERVIEW

2.1 Bone Structure and Function

2.1.1 Cells

2.1.1.1 Osteoblasts

2.1.1.2 Osteocytes

2.1.1.3 Osteoclasts

2.1.2 Tissues

2.1.2.1 Compact Bone

2.1.2.2 Spongy Bone

2.1.2.3 Bone Marrow

2.1.2.4 Endosteum

2.1.2.5 Periosteum

2.1.3 Bone Formation and Resorption

2.1.3.1 In the Fetus

2.1.3.2 In Childhood

2.1.3.3 In Adulthood

2.1.3.4 In Old Age

2.1.3.5 Mechanical Stress and Wolff's Law

2.1.4 Factors Affecting Bone Physiology

2.1.4.1 Age

2.1.4.2 Gender

2.1.4.3 Genetic Disposition

2.1.4.4 Hormonal Activity

2.1.4.5 Physical Activity

2.1.4.6 Cigarette Smoking

2.1.4.7 Alcohol and Caffeine Intake

2.1.4.8 Nutritional Deficiencies

2.1.5 Selected Diseases and Disorders that Affect Bones

2.1.5.1 Fractures

2.1.5.2 Osteoporosis

2.1.5.3 Osteosarcoma

2.1.5.4 Paget's Disease

2.1.5.5 Rickets/Osteomalacia

2.2 Joint Structure and Function

2.2.1 Types of Joints

2.2.1.1 Synarthroses

2.2.1.2 Amphiarthroses

2.2.1.3 Diarthroses

2.2.1.3.1 Ball-and-Socket

2.2.1.3.2 Condyloid

2.2.1.3.3 Hinge

2.2.1.3.4 Gliding

2.2.1.3.5 Pivot

2.2.2 Joint Components

2.2.2.1 Articular Cartilage

2.2.2.2 Bursae

2.2.2.3 Joint Cavity

2.2.2.4 Meniscus

2.2.2.5 Synovial Membrane and Fluid

2.2.2.6 Ligaments and Tendons

2.2.3 Selected Diseases and Disorders that Affect Joints

2.2.3.1 Arthritis

2.2.3.1.1 Osteoarthritis

2.2.3.1.2 Rheumatoid Arthritis

2.2.3.2 Dislocation

2.3.3.3 Ligament and Tendon Injuries

2.3.3.4 Meniscal Injuries

2.3 Management of Bone and Joint Disorders

2.3.1 Fracture Management

2.3.2 Joint Replacement

2.3.3 Arthroscopy

 

Exhibit 2-1: Illustration of Bone Tissue

Exhibit 2-2: Types of Cartilage

Exhibit 2-3: Classifications of Fractures

 

3. BIOMATERIALS IN ORTHOPEDIC AND ARTHROSCOPIC SURGERY APPLICATIONS

3.1 Introduction to Biomaterials

3.1.1 Definition of Biomaterials

3.1.2 Biomaterial Sources

3.1.2.1 Biomaterials Derived from Living Tissues

3.1.2.2 Synthetic Biomaterials

3.1.2.2.1 Organic

3.1.2.2.2 Inorganic

3.1.2.3 Hybrid Biomaterials

3.1.3 Biomaterials and Biocompatibility

3.1.3.1 Nonresorbable Biomaterials

3.1.3.2 Resorbable and Soluble Biomaterials

3.1.3.3 Host Tissue Response to Biomaterials

3.1.4 Tissue Engineering and the Use of Biomaterial Scaffolds

3.1.4.1 Scaffolds for Bone Tissue Regeneration/Repair

3.1.4.2 Scaffolds for Cartilage Tissue Regeneration/Repair

3.1.4.3 Scaffolds for Meniscal Tissue Regeneration/Repair

3.1.4.4 Tissue Engineering Techniques and Bone Growth Factors

3.1.4.5 Tissue Engineering Techniques and Gene Therapy

3.2 Reconstructive Materials

3.2.1 Metals

3.2.1.1 Cobalt Alloys

3.2.1.1.1 Structure and Properties

3.2.1.1.2 Tissue Response

3.2.1.1.3 Advantages and Disadvantages

3.2.1.2 Stainless Steel Alloys

3.2.1.2.1 Structure and Properties

3.2.1.2.2 Tissue Response

3.2.1.2.3 Advantages and Disadvantages

3.2.1.3 Titanium Alloys

3.2.1.3.1 Structure and Properties

3.2.1.3.2 Tissue Response

3.2.1.3.3 Advantages and Disadvantages

3.2.2 Ceramics

3.2.2.1 Aluminum Oxides

3.2.2.1.1 Structure and Properties

3.2.2.2 Calcium Phosphates

3.2.2.2.1 Structure and Properties

3.2.2.3 Glass Ceramics

3.2.2.3.1 Structure and Properties

3.2.2.4 Tissue Response to Ceramic Implant/Coating Materials

3.2.2.5 Advantages and Disadvantages of Ceramic Implant/Coating Materials

3.2.3 Polymers

3.2.3.1 Carbon Fiber

3.2.3.1.1 Structure and Properties

3.2.3.2 Silicone Rubber

3.2.3.2.1 Structure and Properties

3.2.3.3 Polyethylene

3.2.3.3.1 Structure and Properties

3.2.3.4 Polytetrafluoroethylene

3.2.3.4.1 Structure and Properties

3.2.3.5 Polyurethanes

3.2.3.5.1 Structure and Properties

3.2.3.6 Ultrahigh Molecular-Weight Polyethylene

3.2.3.6.1 Structure and Properties

3.2.3.7 Tissue Response to Polymer Implants

3.2.3.8 Advantages and Disadvantages

3.2.4 Resorbable Materials

3.2.4.1 Polyglycolic Acid

3.2.4.2 Polylactic Acid

3.2.4.3 Copolymers

 

Exhibit 3-1: 2006, Selected Synthetic Biomaterials Used in Tissue Engineering and Organ Replacement/Regeneration

Exhibit 3-2: American Society for Testing and Materials D1418 Silicone Rubber Classifications

 

4. ORTHOPEDIC TISSUE GRAFTS MARKET

4.1 Types of Tissue Grafts

4.1.1 Autografts

4.1.1.1 Advantages and Disadvantages of Use

4.1.2 Allografts

4.1.2.1 Advantages and Disadvantages of Use

4.1.3 Xenografts

4.1.3.1 Advantages and Disadvantages of Use

4.2 Bone Allografts

4.2.1 Mechanisms of Bone Graft Activity

4.2.1.1 Osteoconduction

4.2.1.2 Osteogenesis

4.2.1.3 Osteoinduction

4.2.2 Types of Bone Allografts

4.2.2.1 Large and Intercalary Allografts

4.2.2.1.1 Indications for Use

4.2.2.1.2 Products/Technologies

4.2.2.1.3 Placement Volumes Forecast

4.2.2.1.4 Market Forecast

4.2.2.2 Bone Dowels, Pins, Screws, and Wedges

4.2.2.2.1 Indications for Use

4.2.2.2.2 Products/Technologies

4.2.2.2.3 Placement Volumes Forecast

4.2.2.2.4 Market Forecast

4.2.2.3 Machined Cortical Bone Allografts

4.2.2.3.1 Indications for Use

4.2.2.3.2 Products/Technologies

4.2.2.3.3 Placement Volumes Forecast

4.2.2.3.4 Market Forecast

4.2.2.4 Milled and Blended Bone Allografts

4.2.2.4.1 Indications For Use

4.2.2.4.2 Products/Technologies

4.2.2.4.3 Placement Volumes Forecast

4.2.2.4.4 Market Forecast

4.2.2.5 Osteoarticular Allografts

4.2.2.5.1 Indications for Use

4.2.2.5.2 Products/Technologies

4.2.2.5.3 Placement Volumes Forecast

4.2.2.5.4 Market Forecast

4.3 Tendon and Ligament Allografts

4.3.1 Indications for Use

4.3.2 Products/Technologies

4.3.3 Placement Volumes Forecast

4.3.4 Market Forecast

4.4 Meniscus Allografts

4.4.1 Indications for Use

4.4.2 Products/Technologies

4.4.3 Placement Volumes Forecast

4.4.4 Market Forecast

4.5 Orthopedic Tissue Grafts Market Analysis

4.5.1 Market Forecasts

4.5.1.1 Europe

4.5.1.2 France

4.5.1.3 Germany

4.5.1.4 Italy

4.5.1.5 Spain

4.5.1.6 United Kingdom

4.5.1.7 Rest of Europe

4.5.2 Competitive Analysis

4.5.2.1 Europe

4.5.2.2 France

4.5.2.3 Germany

4.5.2.4 Italy

4.5.2.5 Spain

4.5.2.6 United Kingdom

4.5.2.7 Rest of Europe

 

Exhibit 4-1:    Types of Bone Grafts

Exhibit 4-2:    2006, Base Tissue Bone Allografts Used in Orthopedic Surgical Procedures

Exhibit 4-3:    Large and Intercalary Allograft Grafts, Market Forecast, 2004-2010

Exhibit 4-4:    2006, Types of Bioresorbable Fixation Products

Exhibit 4-5:    2006, Selected Bioresorbable Fixation Products

Exhibit 4-6:    Bones, Dowels, Pins, Screws, and Wedges Grafts, Market Forecast, 2004-2010

Exhibit 4-7:    2006, Major Indications for Bone Grafts

Exhibit 4-8:    2006, Selected Machined Cortical Allograft Implant Products

Exhibit 4-9:    Machined Cortical Bone Allografts, Market Forecast, 2004-2010

Exhibit 4-10:  Milled and Blended Bone Allograft Grafts, Market Forecast, 2004-2010

Exhibit 4-11:  Osteoarticular Allograft Grafts, Market Forecast, 2004-2010

Exhibit 4-12:  2006, Selected Emerging Polymer-Based Scaffolds for Ligament and Tendon Repair

Exhibit 4-13:  Tendon and Ligament Allograft Grafts, Market Forecast, 2004-2010

Exhibit 4-14:  2006, Selected Emerging Meniscal Repair and Replacement Products

Exhibit 4-15:  Meniscus Allograft Grafts, Market Forecast, 2004-2010

Exhibit 4-16:  Orthopedic Tissue Grafts, European Market Forecast, 2004-2010

Exhibit 4-17:  Orthopedic Tissue Grafts, France Market Forecast, 2004-2010

Exhibit 4-18:  Orthopedic Tissue Grafts, Germany Market Forecast, 2004-2010

Exhibit 4-19:  Orthopedic Tissue Grafts, Italy Market Forecast, 2004-2010

Exhibit 4-20:  Orthopedic Tissue Grafts, Spain Market Forecast, 2004-2010

Exhibit 4-21:  Orthopedic Tissue Grafts, United Kingdom Market Forecast, 2004-2010

Exhibit 4-22:  Orthopedic Tissue Grafts, Rest of Europe Market Forecast, 2004-2010

Exhibit 4-23:  2005, European Market Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-24:  2005, France Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-25:  2005, Germany Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-26:  2005, Italy Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-27:  2005, Spain Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-28:  2005, United Kingdom Orthopedic Tissue Grafts Market, Share by Supplier

Exhibit 4-29:  2005, Rest of Europe Orthopedic Tissue Grafts Market, Share by Supplier

 

5. BONE GRAFT SUBSTITUTES MARKET

5.1 Bone Graft Substitutes

5.1.1 Calcium Phosphate Formulations

5.1.1.1 Products/Technologies

5.1.1.2 Placement Volumes Forecast

5.1.1.3 Market Forecast

5.1.2 Calcium Sulfate Formulations

5.1.2.1 Products/Technologies

5.1.2.2 Placement Volumes Forecast

5.1.2.3 Market Forecast

5.1.3 Collagen Formulations

5.1.3.1 Products/Technologies

5.1.3.2 Placement Volumes Forecast

5.1.3.3 Market Forecast

5.1.4 Demineralized Bone Matrix Formulations

5.1.4.1 Combination Products

5.1.4.2 Augmentation with Bone Marrow

5.1.4.3 Augmentation with Platelet Concentrate

5.1.4.4 Products/Technologies

5.1.4.5 Placement Volumes Forecast

5.1.4.6 Market Forecast

5.1.5 Hydroxyapatite Formulations

5.1.5.1 Products/Technologies

5.1.5.2 Placement Volumes Forecast

5.1.5.3 Market Forecast

5.1.6 Polymer Products

5.1.6.1 Products/Technologies

5.1.6.2 Placement Volumes Forecast

5.1.6.3 Market Forecast

5.1.7 Composite Formulations

5.1.7.1 Products/Technologies

5.1.7.2 Placement Volumes Forecast

5.1.7.3 Market Forecast

5.2 Bone Graft Substitutes Market Analysis

5.2.1 Market Forecasts

5.2.1.1 Europe

5.2.1.2 France

5.2.1.3 Germany

5.2.1.4 Italy

5.2.1.5 Spain

5.2.1.6 United Kingdom

5.2.1.7 Rest of Europe

5.2.2 Competitive Analysis

5.2.2.1 France

5.2.2.2 Germany

5.2.2.3 Italy

5.2.2.4 Spain

5.2.2.5 United Kingdom

5.2.2.6 Rest of Europe

 

Exhibit 5-1:    Types of Bone Grafts

Exhibit 5-2:    2006, Materials Used in Commercially Available Synthetic Replacement Products

Exhibit 5-3:    Calcium Phosphate Formulations, Market Forecast, 2004-2010

Exhibit 5-4:    Calcium Sulphate Formulations, Market Forecast, 2004-2010

Exhibit 5-5:    2006, Selected Biologically Derived Materials in Collagen Formulations

Exhibit 5-6:    Collagen Formulations, Market Forecast, 2004-2010

Exhibit 5-7:    2006, Selected Demineralized Bone Matrix Products

Exhibit 5-8:    Demineralized Bone Matrix Formulations, Market Forecast, 2004-2010

Exhibit 5-9:    Hydroxyapatite Formulations, Market Forecast, 2004-2010

Exhibit 5-10:  Polymer Products, Market Forecast, 2004-2010

Exhibit 5-11:  Composite Formulations, Market Forecast, 2004-2010

Exhibit 5-12:  Bone Graft Substitutes, European Market Forecast, 2004-2010

Exhibit 5-13:  Bone Graft Substitutes, France Market Forecast, 2004-2010

Exhibit 5-14:  Bone Graft Substitutes, Germany Market Forecast, 2004-2010

Exhibit 5-15:  Bone Graft Substitutes, Italy Market Forecast, 2004-2010

Exhibit 5-16:  Bone Graft Substitutes, Spain Market Forecast, 2004-2010

Exhibit 5-17:  Bone Graft Substitutes, United Kingdom Market Forecast, 2004-2010

Exhibit 5-18:  Bone Graft Substitutes, Rest of Europe Market Forecast, 2004-20010

Exhibit 5-19:  2005, European Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-20:  2005, France Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-21:  2005, Germany Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-22:  2005, Italy Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-23:  2005, Spain Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-24:  2005, United Kingdom Orthopedic Bone Graft Substitutes Market, Share by Supplier

Exhibit 5-25:  2005, Rest of Europe Orthopedic Bone Graft Substitutes Market, Share by Supplier

 

6. BONE GROWTH FACTORS MARKET

6.1 Introduction to Bone Growth Factors

6.1.1 Bone Growth Factor Families

6.1.2 Bone Growth Factor Sources

6.1.3 Mechanisms of Action

6.1.4 Effects on Skeletal Cells and Tissue

6.1.5 Recombinant Bone Growth Factors

6.2 Bone Growth Factor Delivery Vehicles

6.2.1 Reverse-Phase Media

6.2.2 Osteoconductive Matrices

6.2.3 Gene-Activated Matrices

6.2.4 Biodegradable Microspheres

6.2.5 Membrane Barriers

6.2.6 Hydrogels

6.2.7 Products/Technologies

6.2.8 Placement Volumes Forecast

6.2.9 Market Forecast

6.3 Selected Bone Growth Factors

6.3.1 Transforming Growth Factor-β Superfamily of Proteins

6.3.1.1 Transforming Growth Factor

6.3.1.1.1 Clinical Applications

6.3.1.1.2 Products/Technologies

6.3.1.1.3 Placement Volumes Forecast

6.3.1.1.4 Market Forecast

6.3.1.2 Bone Morphogenic Proteins

6.3.1.2.1 Clinical Applications

6.3.1.2.2 Products/Technologies

6.3.1.2.3 Placement Volumes Forecast

6.3.1.2.4 Market Forecast

6.3.2 Fibroblast Growth Factors

6.3.2.1 Clinical Applications

6.3.2.2 Products/Technologies

6.3.2.3 Placement Volumes Forecast

6.3.2.4 Market Forecast

6.3.3 Platelet-Derived Growth Factors

6.3.3.1 Clinical Applications

6.3.3.2 Products/Technologies

6.3.3.3 Placement Volumes Forecast

6.3.3.4 Market Forecast

6.3.4 Bone Marrow Stromal Cell Antigen

6.3.4.1 Clinical Applications

6.3.4.2 Products/Technologies

6.3.4.3 Placement Volumes Forecast

6.3.4.4 Market Forecast

6.3.5 Synthetic Proteins

6.3.5.1 Clinical Applications

6.3.5.2 Products/Technologies

6.3.5.3 Placement Volumes Forecast

6.3.5.4 Market Forecast

6.3.6 Other Growth Factors

6.3.6.1 Insulin-Like Growth Factors

6.3.6.1.1 Clinical Applications

6.3.6.1.2 Products/Technologies

6.3.6.1.3 Placement Volumes Forecast

6.3.6.1.4 Market Forecast

6.3.6.2 LIM Mineralization Protein-1

6.3.6.2.1 Clinical Applications

6.3.6.2.2 Products/Technologies

6.3.6.2.3 Placement Volumes Forecast

6.3.6.2.4 Market Forecast

6.4 Bone Growth Factors Market Analysis

6.4.1 Market Forecasts

6.4.1.1 Europe

6.4.1.2 France

6.4.1.3 Germany

6.4.1.4 Italy

6.4.1.5 Spain

6.4.1.6 United Kingdom

6.4.1.7 Rest of Europe

6.4.2 Competitive Analysis

6.4.2.1 Europe

6.4.2.2 France

6.4.2.3 Germany

6.4.2.4 Italy

6.4.2.5 Spain

6.4.2.6 United Kingdom

6.4.2.7 Rest of Europe

 

Exhibit 6-1:    The TGF-β Superfamily

Exhibit 6-2:    Commonly Known Bone Growth Factors

Exhibit 6-3:    Identified Interleukins

Exhibit 6-4:    Reverse-Phase Media Market Forecast, 2004-2010

Exhibit 6-5:    Osteoconductive Matrices Market Forecast, 2004-2010

Exhibit 6-6:    Gene-Activated Matrices Market Forecast, 2004-2010

Exhibit 6-7:    Biodegradable Microspheres Market Forecast, 2004-2010

Exhibit 6-8:    Membrane Barriers Market Forecast, 2004-2010

Exhibit 6-9:    Hydrogels Market Forecast, 2004-2010

Exhibit 6-10:  The Transforming Growth Factor-Beta Superfamily

Exhibit 6-11:  Bone Growth Factor-B Protein Market Forecast, 2004-2010

Exhibit 6-12:  2006, Selected Bone Morphogenetic Proteins for Orthopedic Applications

Exhibit 6-13:  Bone Morphogenic Proteins Market Forecast, 2004-2010

Exhibit 6-14:  Fibroblast Growth Factors Market Forecast, 2004-2010

Exhibit 6-15:  Platelet-Derived Growth Factors Market Forecast, 2004-2010

Exhibit 6-16:  Bone Marrow Stroma Cell Antigen Market Forecast, 2004-2010

Exhibit 6-17:  Synthetic Proteins Market Forecast, 2004-2010

Exhibit 6-18:  Insulin-Like Growth Factors Market Forecast, 2004-2010

Exhibit 6-19:  LIM Mineralization Protein-1 Market Forecast, 2004-2010

Exhibit 6-20:  Bone Growth Factors, European Market Forecast, 2004-2010

Exhibit 6-21:  Bone Growth Factors, France Market Forecast, 2004-2010

Exhibit 6-22:  Bone Growth Factors, Germany Market Forecast, 2004-2010

Exhibit 6-23:  Bone Growth Factors, Italy Market Forecast, 2004-2010

Exhibit 6-24:  Bone Growth Factors, Spain Market Forecast, 2004-2010

Exhibit 6-25:  Bone Growth Factors, United Kingdom Market Forecast, 2004-2010

Exhibit 6-26:  Bone Growth Factors, Rest of Europe Market Forecast, 2004-2010

Exhibit 6-27:  2005, European Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-28:  2005, France Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-29:  2005, Germany Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-30:  2005, Italy Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-31:  2005, Spain Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-32:  2005, United Kingdom Orthopedic Bone Growth Factors Market, Share by Supplier

Exhibit 6-33:  2005, Rest of Europe Orthopedic Bone Growth Factors Market, Share by Supplier

 

7. ARTHROSCOPIC SURGERY PRODUCTS MARKETS

7.1 Arthroscopic Surgery Procedures

7.1.1 Articular Surface Repair

7.1.2 Ligament Repair

7.1.3 Meniscal Repair

7.1.4 Tendon Repair

7.2 Tissue Fixation Devices

7.2.1 Resorbable Fixation Products

7.2.1.1 Products/Technologies

7.2.1.2 Placement Volumes Forecast

7.2.1.3 Market Forecast

7.2.2 Tissue Fixation Devices Market Analysis

7.2.2.1 Market Forecasts

7.2.2.1.1 Europe

7.2.2.1.2 France

7.2.2.1.3 Germany

7.2.2.1.4 Italy

7.2.2.1.5 Spain

7.2.2.1.6 United Kingdom

7.2.2.1.7 Rest of Europe

7.2.2.2 Competitive Analysis

7.2.2.2.1 Europe

7.2.2.2.2 France

7.2.2.2.3 Germany

7.2.2.2.4 Italy

7.2.2.2.5 Spain

7.2.2.2.6 United Kingdom

7.2.2.2.7 Rest of Europe

7.3 Arthroscopic Suturing Devices

7.3.1 Suture Anchors

7.3.1.1 Resorbable Products

7.3.1.1.1 Products/Technologies

7.3.1.1.2 Placement Volumes Forecast

7.3.1.1.3 Market Forecast

7.3.2 Meniscal Repair Devices

7.3.2.1 Resorbable Products

7.3.2.1.1 Products/Technologies

7.3.2.1.2 Placement Volumes Forecast

7.3.2.1.3 Market Forecast

7.3.3 Arthroscopic Suturing Devices Market Analysis

7.3.3.1 Market Forecasts

7.3.3.1.1 Europe

7.3.3.1.2 France

7.3.3.1.3 Germany

7.3.3.1.4 Italy

7.3.3.1.5 Spain

7.3.3.1.6 United Kingdom

7.3.3.1.7 Rest of Europe

7.3.3.2 Competitive Analysis

7.3.3.2.1 Europe

7.3.3.2.2 France

7.3.3.2.3 Germany

7.3.3.2.4 Italy

7.3.3.2.5 Spain

7.3.3.2.6 United Kingdom

7.3.3.2.7 Rest of Europe

7.4 Viscosupplementation Products

7.4.1 Hyaluronic Acid Formulations

7.4.2 Products and Pricing

7.4.3 Injection Volumes Forecast

7.4.4 Viscosupplementation Products Market Analysis

7.4.4.1 Market Forecasts

7.4.4.1.1 Europe

7.4.4.1.2 France

7.4.4.1.3 Germany

7.4.4.1.4 Italy

7.4.4.1.5 Spain

7.4.4.1.6 United Kingdom

7.4.4.1.7 Rest of Europe

7.4.4.2 Competitive Analysis

7.4.4.2.1 Europe

7.4.4.2.2 France

7.4.4.2.3 Germany

7.4.4.2.4 Italy

7.4.4.2.5 Spain

7.4.4.2.6 United Kingdom

7.4.4.2.7 Rest of Europe

7.5 Autologous Cultured Chondrocytes

7.5.1 Indications for Use

7.5.2 Harvesting Procedures

7.5.3 Culturing Procedures

7.5.4 Implantation Procedures

7.5.5 Products and Pricing

7.5.6 Implantation Volumes Forecast

7.5.7 Autologous Cultured Chondrocyte Products Market Analysis

7.5.7.1 Market Forecasts

7.5.7.1.1 Europe

7.5.7.1.2 France

7.5.7.1.3 Germany

7.5.7.1.4 Italy

7.5.7.1.5 Spain

7.5.7.1.6 United Kingdom

7.5.7.1.7 Rest of Europe

7.5.7.2 Competitive Analysis

7.5.7.2.1 Europe

7.5.7.2.2 France

7.5.7.2.3 Germany

7.5.7.2.4 Italy

7.5.7.2.5 Spain

7.5.7.2.6 United Kingdom

7.5.7.2.7 Rest of Europe

 

Exhibit 7-1:    Surgical Options for Anterior Cruciate Ligament Repair

Exhibit 7-2:    Comparison of Treatment Options for Meniscal Injuries

Exhibit 7-3:    Advantages of Resorbable Fixation Devices

Exhibit 7-4:    Factors Affecting the Properties of Resorbable Polymeric Materials

Exhibit 7-5:    Examples of Resorbable Fixation Devices

Exhibit 7-6:    2006, Selected Bioresorbable Bone Screws, Nails, and Tacks

Exhibit 7-7:    2006, Selected Bioresorbable Interference Screws

Exhibit 7-8:    Reabsorbable Fixation Products Procedure Volumes and Market Forecast, 2004-2010

Exhibit 7-9:    Reabsorbable Fixation Products, European Market Forecast, 2004-2010

Exhibit 7-10:  Reabsorbable Fixation Products, France Market Forecast, 2004-2010

Exhibit 7-11:  Reabsorbable Fixation Products, Germany Market Forecast, 2004-2010

Exhibit 7-12:  Reabsorbable Fixation Products, Italy Market Forecast, 2004-2010

Exhibit 7-13:  Reabsorbable Fixation Products, Spain Market Forecast, 2004-2010

Exhibit 7-14:  Reabsorbable Fixation Products, United Kingdom Market Forecast, 2004-2010

Exhibit 7-15:  Reabsorbable Fixation Products, Rest of Europe Market Forecast, 2004-2010

Exhibit 7-16:  2005, European Tissue Fixation Products Market, Share by Supplier

Exhibit 7-17:  2005, France Tissue Fixation Products Market, Share by Supplier

Exhibit 7-18:  2005, Germany Tissue Fixation Products Market, Share by Supplier

Exhibit 7-19:  2005, Italy Tissue Fixation Products Market, Share by Supplier

Exhibit 7-20:  2005, Spain Tissue Fixation Products Market, Share by Supplier

Exhibit 7-21:  2005, United Kingdom Tissue Fixation Products Market, Share by Supplier

Exhibit 7-22:  2005, Rest of Europe Tissue Fixation Products Market, Share by Supplier

Exhibit 7-23:  2006, Selected Bioresorbable Suture Anchors

Exhibit 7-24:  Arthroscopic Suture Anchors Market Forecast, 2004-2010

Exhibit 7-25:  2006, Selected Resorbable Polymer-Based Devices

Exhibit 7-26:  Meniscal Repair Devices, European Market Forecast, 2004-2010

Exhibit 7-27:  Arthroscopic Suturing Devices, European Market Forecast, 2004-2010

Exhibit 7-28:  Arthroscopic Suturing Devices, France Market Forecast, 2004-2010

Exhibit 7-29:  Arthroscopic Suturing Devices, Germany Market Forecast, 2004-2010

Exhibit 7-30:  Arthroscopic Suturing Devices, Italy Market Forecast, 2004-2010

Exhibit 7-31:  Arthroscopic Suturing Devices, Spain Market Forecast, 2004-2010

Exhibit 7-32:  Arthroscopic Suturing Devices, United Kingdom, Market Forecast, 2004-2010

Exhibit 7-33:  Arthroscopic Suturing Devices, Rest of Europe, Market Forecast, 2004-2010

Exhibit 7-34:  2005, European Arthroscopic Devices Market, Share by Supplier

Exhibit 7-35:  2005, France Arthroscopic Devices Market, Share by Supplier

Exhibit 7-36:  2005, Germany Arthroscopic Devices Market, Share by Supplier

Exhibit 7-37:  2005, Italy Arthroscopic Devices Market, Share by Supplier

Exhibit 7-38:  2005, Spain Arthroscopic Devices Market, Share by Supplier

Exhibit 7-39:  2005, United Kingdom Arthroscopic Devices Market, Share by Supplier

Exhibit 7-40:  2005, Rest of Europe Arthroscopic Devices Market, Share by Supplier

Exhibit 7-41:  Effects of Hyaluronic Acid Therapy

Exhibit 7-42:  2006, Selected Current and Emerging Viscosupplementation Products

Exhibit 7-43:  Viscosupplementation Procedure Volumes and Market Forecast, 2004-2010

Exhibit 7-44:  Viscosupplementation Products, European Market Forecast, 2004-2010

Exhibit 7-45:  Viscosupplementation Products, France Market Forecast, 2004-2010

Exhibit 7-46:  Viscosupplementation Products, Germany Market Forecast, 2004-2010

Exhibit 7-47:  Viscosupplementation Products, Italy Market Forecast, 2004-2010

Exhibit 7-48:  Viscosupplementation Products, Spain Market Forecast, 2004-2010

Exhibit 7-49:  Viscosupplementation Products, United Kingdom Market Forecast, 2004-2010

Exhibit 7-50:  Viscosupplementation Products, Rest of Europe Market Forecast, 2004-2010

Exhibit 7-51:  2005, European Viscosupplementation Products Market, Share by Supplier

Exhibit 7-52:  2005, France Viscosupplementation Products Market, Share by Supplier

Exhibit 7-53:  2005, Germany Viscosupplementation Products Market, Share by Supplier

Exhibit 7-54:  2005, Italy Viscosupplementation Products Market, Share by Supplier

Exhibit 7-55:  2005, Spain Viscosupplementation Products Market, Share by Supplier

Exhibit 7-56:  2005, United Kingdom Viscosupplementation Products Market, Share by Supplier

Exhibit 7-57:  2005, Rest of Europe Viscosupplementation Products Market, Share by Supplier

Exhibit 7-58:  2006, Selected Autologous Growth Factor Products

Exhibit 7-59:  Autologous Cultured Chondrocytes Market Forecast, 2004-2010

Exhibit 7-60:  Autologous Cultured Chondrocytes, European Market Forecast, 2004-2010

Exhibit 7-61:  Autologous Cultured Chondrocytes, France Market Forecast, 2004-2010

Exhibit 7-62:  Autologous Cultured Chondrocytes, Germany Market Forecast, 2004-2010

Exhibit 7-63:  Autologous Cultured Chondrocytes, Italy Market Forecast, 2004-2010

Exhibit 7-64:  Autologous Cultured Chondrocytes, Spain Market Forecast, 2004-2010

Exhibit 7-65:  Autologous Cultured Chondrocytes, United Kingdom Market Forecast 2004-2010

Exhibit 7-66:  Autologous Cultured Chondrocytes, Rest of Europe Market Forecast, 2004-2010

Exhibit 7-67:  2005, European Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-68:  2005, France Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-69:  2005, Germany Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-70:  2005, Italy Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-71:  2005, Spain Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-72:  2005, United Kingdom Autologous Cultured Chondrocyte Products Market, Share by Supplier

Exhibit 7-73:  2005, Rest of Europe Autologous Cultured Chondrocyte Products Market, Share by Supplier

 

8. COMPANY PROFILES

8.1   Biomet Europe/Biomet, Inc.

8.2   Bioniche Pharma Group LTD

8.3   Chiesi Farmaceutici SPA

8.4   DePuy Spine, Inc./Johnson & Johnson

8.5   FIDIA Group

8.6   Genzyme Biosurgery Corporation/Genzyme Corporation

8.7   Harvest Technologies Corporation

8.8   Isotis OrthoBiologics, Inc./IsoTis SA

8.9   Linvatec Corporation/ConMED Corporation

8.10 Walter Lorenz Surgical, Inc./Biomet, Inc.

8.11 Medtronic, Inc.

8.12 DePuy Mitek, Inc./Johnson & Johnson

8.13 Orthovita, Inc.

8.14 Osteotech, Inc

8.15 Smith & Nephew PLC

8.16 Stryker Biotech/Stryker Corporation

8.17 Sulzer Innotec AG

8.18 Synthes, Inc./Synthes AG

8.19 Verigen Transplantation Services LTD/Verigen AG

8.20 Wright Medical Technology, Inc./Wright Medical Group

8.21 Zimmer Holdings Inc.

 

APPENDIX:  COMPANY LISTING



COMPANIES COVERED:

  1. Anika Therapeutics, Inc.
  2. ARS ARTHRO AG
  3. Arthrex, Inc.
  4. Biocomposites LTD
  5. Biomet, Inc.
  6. Bioniche Life Sciences, Inc.
  7. BioTissue Technologies GmbH/The BioTissue Group
  8. co.don AG
  9. ConMed Corporation
  10. Genzyme Corporation
  11. Interface Biotech AS
  12. Johnson & Johnson
  13. Regeneration Technologies, Inc.
  14. Smith & Nephew PLC
  15. Stryker Corporation
  16. TETEC AG
  17. Tyco International LTD
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