TRENDS AND OPPORTUNITIES IN U.S. ORTHOPEDIC MARKETS FOR IMPLANT, RECONSTRUCTION, AND TRAUMA PRODUCTS

360 Pages | 96 Exhibits | 2004 Analysis | Forecasts Through 2012 Product Family: Market Reports




OVERVIEW:
According to the American Academy of Orthopedic Surgeons, approximately 28.6 million people in the United States sustain some type of musculoskeletal injury annually, at a cost of approximately $254 billion. Many orthopedic reconstruction and trauma device manufacturers have experienced significant growth in the past several years. This robust growth is due to a number of factors including demographics and the aging population, improved technologies, and upward pricing of implants and devices. The market for joint replacement products, fracture fixation products, bioresorbable fixation products, bone growth stimulation products, bone replacement products, and orthobiologics was estimated at $5.4 billion in 2002. This market is expected to grow at a compound annual rate of 10.2% to $14.2 billion in the year 2012.

This dynamic report from Medtech Insight includes analyses of products, technologies, current and forecast markets, competitors, and opportunities in the U.S. markets for orthopedic implant, reconstruction, and trauma products.

Topics discussed in this report include the structure of bones and joints, illnesses and injuries affecting bone and joint tissue, allogeneic and synthetic bone replacement materials, bioresorbable fixation devices, bone cements and accessories, bone growth factors, bone growth stimulation systems, fracture repair procedures, joint implant procedures, and stem cell and gene therapy.

TABLE OF CONTENTS:

EXECUTIVE SUMMARY

i.   Joint Replacement Products Market

ii.   Fracture Fixation Products Market

iii.  Bioresorbable Fixation Products Market

iv.  Bone Growth Stimulation Products Market

v.  Bone Replacement Products Market

vi.  Orthobiologics Products Market

vii. Combined Market Forecast

 

1. CLINICAL OVERVIEW OF BONES AND JOINTS

1.1 Bone and Joint Structure

1.1.1 Bone Tissue

1.1.1.1 Cancellous and Cortical Bone

1.1.1.2 Diaphysis and Epiphysis

1.1.1.3 Endosteum

1.1.1.4 Hydroxyapatite and Osteogenesis

1.1.1.5 Periosteum

1.1.2 Cartilage

1.1.3 Ligaments and Tendons

1.1.4 Joint Structures

1.1.4.1 Ankle

1.1.4.2 Elbow

1.1.4.3 Finger and Thumb

1.1.4.4 Hip

1.1.4.5 Knee

1.1.4.6 Shoulder

1.1.4.7 Wrist

1.1.5 Peripheral Vascular and Neural Structures

1.2 Chondrogenesis and Osteogenesis

1.2.1 Bone Formation and Remodeling

1.2.2 Tissue Repair

1.3 Illnesses and Injuries Affecting Bone and Joint Tissue

1.3.1 Arthritis

1.3.1.1 Osteoarthritis

1.3.1.2 Rheumatoid Arthritis

1.3.2 Osteoporosis

1.3.3 Bone Fractures

1.3.4 Cartilage Injuries

1.3.5 Ligament Injuries

 

2. JOINT REPLACEMENT PRODUCTS MARKET

2.1 Materials and Processes that Reduce Wear Debris

2.1.1 Minimally Invasive Surgery

2.1.2 Computer-Assisted Surgery

2.2 Hip Implants

2.2.1 Implant Procedure Types

2.2.2 Hip Replacement

2.2.3 Products

2.3 Knee Implants

2.3.1 Implant Procedure Types

2.3.2 Knee Replacement

2.3.3 Products

2.4 Shoulder Implants

2.4.1 Implant Procedure Types

2.4.2 Shoulder Replacement

2.4.3 Products

2.5 Small Joint Implants

2.5.1 Small Joint Replacement

2.5.1.1 Elbow

2.5.1.2 Wrist

2.5.1.3 Digit

2.5.1.4 Ankle

2.5.2 Products

2.5.2.1 Elbow

2.5.2.2 Wrist

2.5.2.3 Digit

2.5.2.4 Ankle

2.6 Bone Cements

2.6.1 Products

2.7 Market Analyses

2.7.1 Hip Replacement Products Market

2.7.1.1 Market Forecast

2.7.1.2 Competitive Analysis

2.7.2 Knee Replacement Products Market

2.7.2.1 Market Forecast

2.7.2.2 Competitive Analysis

2.7.3 Shoulder Replacement Products Market

2.7.3.1 Market Forecast

2.7.3.2 Competitive Analysis

2.7.4 Small Joint Replacement Products Market

2.7.4.1 Market Forecast

2.7.4.2 Competitive Analysis

2.7.5 Bone Cements Market

2.7.5.1 Market Forecast

2.7.5.2 Competitive Analysis

2.8 Combined Market Forecast

 

3. FRACTURE FIXATION PRODUCTS MARKET

3.1 Fracture Repair

3.1.1 Dynamic Fixation

3.1.2 Static Fixation

3.2 Fracture Repair Procedures

3.3 Internal Fixation

3.3.1 Device Types

3.3.1.1 Hip Screws

3.3.1.2 Intramedullary Nails or Rods

3.3.1.3 Plates and Screws

3.3.1.4 Screws, Pins, and Wires

3.3.2 Products

3.3.3 Market Forecast

3.3.4 Competitive Analysis

3.4 External Fixation

3.4.1 Products

3.4.2 Market Forecast

3.4.3 Competitive Analysis

3.5 Combined Market Forecast

 

4. BIORESORBABLE FIXATION PRODUCTS MARKET

4.1 Synthetic Polymers

4.2 Cadaver Bone

4.3 Products

4.3.1 Bioresorbable Pins

4.3.2 Bioresorbable Bone Nails, Screws, and Tacks

4.3.3 Bioresorbable Interference Screws

4.3.4 Bioresorbable Suture Anchors

4.3.5 Bioresorbable Meniscal Repair Devices

4.4 Market Forecast

4.4.1 Shoulder Reconstruction Market

4.4.2 Meniscal Repair Market

4.4.3 Small Joint/Bone Fragment Fixation Market

4.4.4 Cruciate Ligament Fixation Market

4.5 Competitive Analysis

 

5. BONE GROWTH STIMULATION PRODUCTS MARKET

5.1 Electromagnetic Bone Growth Stimulation

5.1.1 Pulsed Electromagnetic Field Stimulation

5.1.2 Capacitive Coupling Stimulation

5.1.3 Combined Magnetic Field Stimulation

5.1.4 Low Intensity, Pulsed Ultrasound Stimulation

5.1.5 Direct Current Electrical Stimulation

5.2 Products

5.3 Market Forecast

5.4 Competitive Analysis

 

6. BONE REPLACEMENT PRODUCTS MARKET

6.1 Bone Replacement Materials

6.1.1 Autografts

6.1.2 Allografts

6.1.2.1 Base Tissue Products

6.1.2.2 Machined Implant Products

6.1.2.3 Demineralized Bone Matrix Products

6.1.2.4 Composite Implant Products

6.1.3 Synthetic Materials

6.1.3.1 Hydroxyapatite

6.1.3.2 Calcium Phosphate and Calcium Sulfate

6.1.3.3 Polymethylmethacrylate Cement

6.2 Products

6.2.1 Demineralized Bone Matrix Products

6.2.2 Synthetic Products

6.3 Indications for Bone Grafts

6.3.1 Major Orthopedic Indications

6.3.1.1 Fracture Repair

6.3.1.2 Revision Joint Procedures

6.3.1.3 Bone Cysts and Tumors

6.3.2 Spinal Indications

6.4 Bone Grafting

6.5 Market Analysis

6.5.1 Market Forecast

6.5.2 Competitive Analysis

 

7. ORTHOBIOLOGICS PRODUCTS MARKET

7.1 Bone Growth Factors

7.1.1 Transforming Growth Factor-Beta

7.1.1.1 Bone Morphogenetic Proteins

7.1.1.1.1 Recombinant Bone Morphogenetic Protein Technologies

7.1.2 Insulin-Like Growth Factor-I

7.1.3 Fibroblast Growth Factors

7.1.4 Allogeneic-Derived Growth Factors

7.1.5 Autologous Growth Factors

7.1.6 Recombinant Platelet-Derived Growth Factor

7.2 Small Molecules

7.3 Stem Cell and Gene Therapy

7.4 Market Analysis

7.5 Competitive Analysis

7.6 Combined Market Forecast

 

8. COMPANY PROFILES

8.1   Arthrex, Inc.

8.2   Biomet, Inc.

8.3   ConMed Corporation

8.4   Interpore Cross International, Inc.

8.5   Johnson & Johnson

8.6   Medtronic, Inc.

8.7   Orthofix International NV

8.8   Orthovita, Inc.

8.9   Osteotech, Inc.

8.10 Regeneration Technologies, Inc.

8.11 Smith & Nephew PLC

8.12 Stryker Corporation

8.13 Synthes-Stratec, Inc.

8.14 Wright Medical Technology, Inc.

8.15 Zimmer Holdings, Inc.

 

APPENDIX:  COMPANY LISTING

 

LIST OF EXHIBITS

 

Exhibit ES-1:  Joint Replacement Products, Market Forecast, 2002-2012

Exhibit ES-2:  Fracture Fixation Products, Market Forecast, 2002-2012

Exhibit ES-3:  Bioresorbable Fixation Products, Market Forecast, 2002-2012

Exhibit ES-4:  Bone Growth Stimulation Systems, Market Forecast, 2002-2012

Exhibit ES-5:  Allogeneic and Synthetic Bone Replacement Products, Market Forecast, 2002-2012

Exhibit ES-6:  Orthobiologics Products, Market Forecast, 2002-2012

Exhibit ES-7:  Orthopedic Products for Implant, Reconstruction, and Trauma, Market Forecast, 2002-2012

 

Exhibit 1-1:    Illustration of Bone Tissue

Exhibit 1-2:    Types of Cartilage

Exhibit 1-3:    Osteoarthritis, Facts and Figures, 1996-2002

Exhibit 1-4:    Rheumatoid Arthritis, Facts and Figures, 1996-2002

Exhibit 1-5:    Osteoporosis, Facts and Figures, 1996-2002

Exhibit 1-6:    2002, Incidence of Osteoporosis-Related Fractures, by Site

Exhibit 1-7:    Classifications of Fractures

 

Exhibit 2-1:    2004, Selected Cross-Linked Polyethylenes Used in Orthopedic Implants

Exhibit 2-2:    2004, Selected Polyethylene-Alternative Bearings Used in Hip Implants

Exhibit 2-3:    2004, Selected Orthopedic Computer-Assisted Surgery Systems

Exhibit 2-4:    2004, Selected Hip Replacement Systems

Exhibit 2-5:    2004, Selected Knee Replacement Systems

Exhibit 2-6:    2004, Selected Shoulder Replacement Systems

Exhibit 2-7:    2004, Selected Elbow Replacement Systems

Exhibit 2-8:    2004, Selected Wrist Replacement Systems

Exhibit 2-9:    2004, Selected Digit Replacement Systems

Exhibit 2-10:  2004, Selected Ankle Replacement Systems

Exhibit 2-11:  2004, Selected Bone Cements

Exhibit 2-12:  Factors Affecting the Implants Market

Exhibit 2-13:  Reconstruction Implants, Market Forecast, 2002-2012

Exhibit 2-14:  Primary, Partial, and Revision Hip Implants, Market Forecast, 2002-2012

Exhibit 2-15:  2002, Hip Implants Market, Share by Supplier

Exhibit 2-16:  Primary, Unicompartmental, and Revision Knee Implants, Market Forecast, 2002-2012

Exhibit 2-17:  2002, Knee Implants Market, Share by Supplier

Exhibit 2-18:  Shoulder Implants, Market Forecast, 2002-2012

Exhibit 2-19:  2002, Shoulder Implants Market, Share by Supplier

Exhibit 2-20:  Small Joint Implants, Market Forecast, 2002-2012

Exhibit 2-21:  2002, Digit Implants Market, Share by Supplier

Exhibit 2-22:  2002, Elbow Implants Market, Share by Supplier

Exhibit 2-23:  Bone Cements and Accessories Used in Implants and Other Procedures, Market Forecast, 2002-2012

Exhibit 2-24:  2002, Bone Cements Market, Share by Supplier

Exhibit 2-25:  Joint Replacement Products, Combined Market Forecast, 2002-2012

 

Exhibit 3-1:    2002, Fracture Repair Procedures

Exhibit 3-2:    Advantages and Disadvantages of Internal Fixation Devices

Exhibit 3-3:    2004, Selected Internal Fixation Devices

Exhibit 3-4:    Internal Fixation Devices, Market Forecast, 2002-2012

Exhibit 3-5:    Hip Screws; Intramedullary Nails; Plates and Screws; and Screws, Pins, and Wires, Market Forecast, 2002-2012

Exhibit 3-6:    2002, Internal Fixation Devices Market, Share by Supplier

Exhibit 3-7:    2002, Hip Screws Market, Share by Supplier

Exhibit 3-8:    2002, Intramedullary Nails Market, Share by Supplier

Exhibit 3-9:    2002, Plates and Screws Market, Share by Supplier

Exhibit 3-10:  2002, Screws, Pins, and Wires Market, Share by Supplier

Exhibit 3-11:  Advantages and Disadvantages of External Fixation Devices

Exhibit 3-12:  2004, Selected External Fixation Devices

Exhibit 3-13:  External Fixation Devices, Market Forecast, 2002-2012

Exhibit 3-14:  2002, External Fixation Devices Market, Share by Supplier

Exhibit 3-15:  Fracture Fixation Products, Combined Market Forecast, 2002-2012

 

Exhibit 4-1:    Factors Affecting the Properties of Bioresorbable Polymeric Materials

Exhibit 4-2:    Selected Bioresorbable Fixation Products

Exhibit 4-3:    2004, Selected Bioresorbable Pins

Exhibit 4-4:    2004, Selected Bioresorbable Bone Nails, Screws, and Tacks

Exhibit 4-5:    2004, Selected Bioresorbable Interference Screws

Exhibit 4-6:    2004, Selected Bioresorbable Suture Anchors

Exhibit 4-7:    2004, Selected Bioresorbable Polymer-Based Devices for Meniscal Repair

Exhibit 4-8:    2002, Bioresorbable Fixation Products Market

Exhibit 4-9:    Bioresorbable Fixation Products, Market Forecast, 2002-2012

Exhibit 4-10:  2002, Rotator Cuff Repair, Treatment Approaches

Exhibit 4-11:  2002, Bioresorbable Fixation Products Market, Share by Supplier

 

Exhibit 5-1:    2004, Selected Bone Growth Stimulation Systems

Exhibit 5-2:    Bone Growth Stimulation Therapy, Procedure Volumes Forecast, 2002-2012

Exhibit 5-3:    Bone Growth Stimulation Systems, Market Forecast, 2002-2012

Exhibit 5-4:    2002, Bone Growth Stimulation Systems Market, Share by Supplier

 

Exhibit 6-1:    Types of Bone Grafts

Exhibit 6-2:    2004, Materials Used in Synthetic Bone Replacement Products

Exhibit 6-3:    2004, Base Tissue Bone Allografts Used in Orthopedic Surgical Procedures, by Type

Exhibit 6-4:    2004, Selected Demineralized Bone Matrix Products

Exhibit 6-5:    2004, Selected Synthetic Bone Replacement Products

Exhibit 6-6:    2004, Major Indications for Bone Grafts

Exhibit 6-7:    2002, Fracture Procedures Employing Bone Grafts

Exhibit 6-8:    2002, Revision Joint Procedures Employing Bone Grafts

Exhibit 6-9:    2002, Bone Cyst and Tumor Procedures Employing Bone Grafts

Exhibit 6-10:  2002, Spinal Surgical Procedures Employing Bone Grafts

Exhibit 6-11:  2002, Orthopedic and Spinal Surgical Procedures Employing Bone Grafts

Exhibit 6-12:  2002, Bone Replacement Products, Share by Type

Exhibit 6-13:  Allogeneic and Synthetic Bone Replacement Products, Market Forecast, 2002-2012

Exhibit 6-14:  2002, Demineralized Bone Matrix Products Market, Share by Supplier

Exhibit 6-15:  2002, Synthetic Bone Replacement Products Market, Share by Supplier

 

Exhibit 7-1:    The Transforming Growth Factor-Beta Superfamily

Exhibit 7-2:    2004, Selected Bone Morphogenetic Proteins for Orthopedic Applications

Exhibit 7-3:    INFUSE Bone Graft versus Iliac Crest Bone Graft for Lumbar Fusion, at 24-Month Follow-Up

Exhibit 7-4:    2004, Selected Growth Factors for Orthopedic Applications

Exhibit 7-5:    Growth Factors versus Gene Therapy in Bone Repair

Exhibit 7-6:    2004, Gene Therapy Delivery Methods for Bone Repair

Exhibit 7-7:    2004, Selected Orthopedic Stem Cell and Gene Therapy Products

Exhibit 7-8:    Fracture Repair and Spinal Fusion, Potential Procedure Volumes Forecast, 2002-2012

Exhibit 7-9:    Bone Morphogenetic Proteins, Market Forecast, 2002-2012

Exhibit 7-10:  Autologous Growth Factors, Market Forecast, 2002-2012

Exhibit 7-11:  2002, Autologous Growth Factors, Share by Supplier

Exhibit 7-12:  Orthobiologics Products, Combined Market Forecast, 2002-2012



COMPANIES COVERED:

  1. Arthrex, Inc.
  2. Biomet, Inc.
  3. ConMed Corporation
  4. Interpore Cross International, Inc.
  5. Johnson & Johnson
  6. Medtronic, Inc.
  7. Orthofix International NV
  8. Orthovita, Inc.
  9. Osteotech, Inc.
  10. Regeneration Technologies, Inc.
  11. Smith & Nephew PLC
  12. Stryker Corporation
  13. Synthes-Stratec, Inc.
  14. Wright Medical Technology, Inc.
  15. Zimmer Holdings, Inc.
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